NCT04378218 (HIIT) is a NA clinical trial of High Intensity Interval Training (HIIT) in Paraplegia, Spinal, sponsored by Mayo Clinic.

Who is sponsoring NCT04378218?

NCT04378218 is sponsored by Mayo Clinic.

What drugs are being tested in NCT04378218?

Interventions in NCT04378218: High Intensity Interval Training (HIIT).

What condition does NCT04378218 study?

NCT04378218 studies Paraplegia, Spinal, Spinal Cord Trauma.

Is NCT04378218 still recruiting?

NCT04378218 is currently completed. Last updated 20 August 2021.

Last reviewed 2021-08-20 · How we verify

NCT04378218: HIIT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cardiovascular Effects of High Intensity Interval Training in Individuals With Paraplegia

Completed NA Last updated 20 August 2021

What this trial tests

NA trial testing High Intensity Interval Training (HIIT) in Paraplegia, Spinal in 10 participants. Completed in 16 July 2021.

Timeline

12 December 2019

Primary endpoint
16 July 2021

16 July 2021

Quick facts

Lead sponsor	Mayo Clinic
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	health services research
Enrollment	10
Start date	12 December 2019
Primary completion	16 July 2021
Estimated completion	16 July 2021
Sites	1 location across United States

Drugs / interventions tested

High Intensity Interval Training (HIIT)

Conditions studied

Paraplegia, Spinal — all drugs for Paraplegia, Spinal →
Spinal Cord Trauma — all drugs for Spinal Cord Trauma →

Sponsor

Mayo Clinic

Who can join

18 and older, any sex, with Paraplegia, Spinal or Spinal Cord Trauma. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study seeks to determine whether high intensity interval training has an effect on cardiovascular parameters in wheelchair users with paraplegia.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

At-Home High-Intensity Interval Training for Individuals with Paraplegia Following Spinal Cord Injury: A Case Series.
Webb KL, Linde MB, Veith DD, Morkeberg OH, et al · · 2025 · PMID 41809409 · DOI 10.33696/rehabilitation.7.056
Academy of Spinal Cord Injury Professionals 2022 ASCIP Hybrid Educational Conference & Expo September 7 – 10 Kansas City, MO, POSTER ABSTRACTS P1–P25
POSTER ABSTRACTS 1- 48: 2021 ASCIP Hybrid Educational Conference & Expo

Verify or expand the search:

Other trials of High Intensity Interval Training (HIIT)

Trials testing the same drug.

NCT06831266 — Effects of Exercise Prediabetic Individuals · NA · recruiting
NCT06551441 — Cardiopulmonary Adaptations to High-intensity Interval Training (HIIT) in COPD · NA · recruiting
NCT06609954 — "COMPARATIVE EFFECTS of REDUCED EXERTION HIGH INTENSITY TRAINING (REHIT) VERSUS HIGH INTENSITY INTERVAL TRAINING (HIIT) · NA · active not recruiting
NCT06610006 — Combined Effects of Isometric Wall Squats and High Intensity Interval Training on Rate Pressure Product in Normotensive · NA · active not recruiting
NCT06059872 — Biomarkers of Reaction To HIIT Exercise · NA · recruiting

Other recruiting trials for Paraplegia, Spinal

Currently open trials in the same condition.

NCT06272279 — Neuromodulation With Spinal Stimulation Methods · NA · recruiting

Other Mayo Clinic trials

Trials by the same sponsor.

NCT07126548 — A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men · NA · not yet recruiting
NCT07221656 — Evaluation of Prolonged Asparaginase Activity Levels After Calaspargase Pegol Administration · not yet recruiting
NCT06891001 — The Utilization of a Shoe Insert on Individuals With Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, · NA · not yet recruiting
NCT07169799 — Impact of Cryotherapy Spray (Tru-Freeze) for the Eradication of Gastric Antral Vascular Ectasia (ICE-GAVE) · NA · recruiting
NCT07086183 — Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04378218 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
Last refreshed: 20 August 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04378218.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing