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NCT04377542
RCT on LIFT Versus Modified Parks Technique Versus Two-Stage Seton
NA trial testing LIFT in Anal Fistula in 66 participants. Status unknown.
1 December 2019
Quick facts
| Lead sponsor | Mansoura University |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 66 |
| Start date | 1 January 2019 |
| Primary completion | 1 December 2019 |
| Estimated completion | 30 June 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- LIFT
- Parks
- Seton
Conditions studied
- Anal Fistula — all drugs for Anal Fistula →
Sponsor
Mansoura University
Who can join
Adults 18 to 65, any sex, with Anal Fistula. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
LIFT is a sphincter-saving procedure that is based on the concept of secure closure of the internal opening and concomitant removal of infected cryptoglandular tissue in the intersphincteric plane. Modified Parks technique involves adequate drainage of the intersphincteric space by extending the internal anal sphincterotomy. Placement of seton in the fistula track has been used for a long time and is still being currently used. Drainage two-stage seton is used to promote adequate drainage of infection and can be employed as a definitive treatment of anal fistula. This present randomized study aimed to compare LIFT, modified Parks technique, and two-stage seton in treatment of complex anal fistula in terms of success of treatment and complication rates.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04377542
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of LIFT
Trials testing the same drug.
- NCT04616911 — Rerouting Seton Versus LIFT for Complex Anal Fistula · NA · unknown
- NCT05134168 — LIFT With or Without Injection of BM-MNCs · NA · completed
- NCT06616662 — Transsphincteric Fistula Management Using LIFT and MAF · completed
- NCT04351074 — Ligation of Intersphincteric Track (LIFT) Versus Fistulectomy in Trans-sphincteric Anal Ffistula. · NA · completed
- NCT06212739 — Post-op Pain After Fistula Laser Closure or Ligation of the Intersphincteric Tract for Anal Fistula · NA · completed
Other recruiting trials for Anal Fistula
Currently open trials in the same condition.
- NCT07477496 — Recurrence and Anal Fistula Patient Reported Outcomes Trial · recruiting
- NCT07081373 — Study on Repeat Liposomal Bupivacaine for Post-Surgery Pain in Anal Fistula Patients. · NA · recruiting
- NCT06803550 — Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions · NA · recruiting
- NCT06303752 — Tissue Therapy of Transsphincteric Anal Fistula · Phase 1, PHASE2 · recruiting
- NCT05641844 — A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal · NA · recruiting
Other Mansoura University trials
Trials by the same sponsor.
- NCT05785377 — Neostigmine as an Adjuvant in Tranversus Abdominis Plane (TAP) Block in Cesarean Section Under Spinal Anesthesia · NA · not yet recruiting
- NCT07509567 — Conventional Palatal Crib Versus Bonded Spurs for Anterior Open Bite Treatment · NA · not yet recruiting
- NCT07393178 — Efficacy & Safety of High Power vs. Low Power Holmium Laser in Mini-PCNL for Large Renal Stones · NA · not yet recruiting
- NCT07436182 — Mitochondrial Redox Modulation in Newly Diagnosed Type 2 Diabetes: A Randomized Controlled Trial Comparing Imeglimin vs. · Phase 4 · not yet recruiting
- NCT07534943 — Effectiveness of Oleanolic Acid as Intracanal Medicament on Infectious/Inflammatory Contents in Teeth With Apical Period · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04377542 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mansoura University
- Last refreshed: 6 May 2020
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