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NCT04375969
Short to Long Effects of Whole Body Cryostimulation on Insulin Sensitivity Among Overweight
NA trial testing whole body cryostimulation treatment in Cryotherapy in 80 participants. Status unknown.
30 December 2019
Quick facts
| Lead sponsor | Gdansk University of Physical Education and Sport |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 80 |
| Start date | 3 January 2018 |
| Primary completion | 30 December 2019 |
| Estimated completion | 30 December 2021 |
| Sites | 1 location across Poland |
Drugs / interventions tested
- whole body cryostimulation treatment
- Connection WBC treatment and HIIT training
- Control Group — full drug profile →
- HIIT training group
Conditions studied
- Cryotherapy — all drugs for Cryotherapy →
- Training — all drugs for Training →
- Overweight — all drugs for Overweight →
- Insulin — all drugs for Insulin →
Sponsor
Gdansk University of Physical Education and Sport
Who can join
Adults 20 to 65, any sex, with Cryotherapy or Training. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Therapeutic effectiveness of coldness in relieving pain and reducing inflammation has been known for many years now. Over that time, various coldness therapies have gained in popularity, including winter swimming, snow baths or whole body cryostimulation (WBC) . Recent researches have shown positive effects of WBC on metabolic profile, low-to-moderate chronic inflammation and related diseases (e.g., obesity). WBC could be, thus, intended as an adjuvant method in the treatment of dysmetabolic conditions, such as overweight or obesity. WBC is a cheap easily accessible practice, with a few well-defined contraindications and limited non severe possible adverse events, if performed in specialized centres. At the same time, in sport science appears data, which indicated on inhibition of adaptive changes induced by regular training. The primary aim is to define, through a randomized controlled approach, the relative effectiveness of up to 20 consecutive sessions of either WBC, high-intensity intermittent training (HIIT), or their combination (WBC and HIIT) in improving the metabolic status of overweight and obese subjects. The effects will be assessed, at different time-points, in terms of insulin sensitivity and modification in the profile of hormones regulating the energy metabolism (adipokines, myokines, bone-derived hormones) and the inter-organ cross-talk.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Beneficial effects of whole-body cryotherapy on glucose homeostasis and amino acid profile are associated with a reduced myostatin serum concentration.
Kozłowska M, Kortas J, Żychowska M, Antosiewicz J, et al · · 2021 · cited 11× · PMID 33782504 · DOI 10.1038/s41598-021-86430-9
Verify or expand the search:
- PubMed search for NCT04375969
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04375969 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Gdansk University of Physical Education and Sport
- Last refreshed: 11 May 2021
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