NCT04374383 is a Phase 2 clinical trial of Phthalocyanine Dye in Periodontitis, sponsored by SVS Institute of Dental Sciences.

Who is sponsoring NCT04374383?

NCT04374383 is sponsored by SVS Institute of Dental Sciences.

What drugs are being tested in NCT04374383?

Interventions in NCT04374383: Phthalocyanine Dye, LASER assisted SRP.

What condition does NCT04374383 study?

NCT04374383 studies Periodontitis, Alveolar Bone Loss.

Is NCT04374383 still recruiting?

NCT04374383 is currently status unknown. Last updated 5 May 2020.

Last reviewed 2020-05-05 · How we verify

NCT04374383

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Effects of a Single Application of a Novel Photosensitizer in The Treatment of Chronic Periodontitis - A Randomized Controlled Trial

Status unknown Phase 2 Last updated 5 May 2020

What this trial tests

Phase 2 trial testing Phthalocyanine Dye in Periodontitis in 26 participants. Status unknown.

Timeline

1 June 2019

Primary endpoint
1 November 2020

1 November 2021

Quick facts

Lead sponsor	SVS Institute of Dental Sciences
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	26
Start date	1 June 2019
Primary completion	1 November 2020
Estimated completion	1 November 2021
Sites	2 locations across India

Drugs / interventions tested

Phthalocyanine Dye — full drug profile →
LASER assisted SRP — full drug profile →

Conditions studied

Periodontitis — all drugs for Periodontitis →
Alveolar Bone Loss — all drugs for Alveolar Bone Loss →

Sponsor

SVS Institute of Dental Sciences

Who can join

Adults 30 to 60, any sex, with Periodontitis or Alveolar Bone Loss. Healthy volunteers can join.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

Release profile of the drug
Time frame: Change from baseline to 7-days.
Release profile of the drug in Gingival Crevicular Fluid (GCF) samples will be evaluated through biochemical testing kits.
probing pocket depths (PPD)
Time frame: Change from baseline to 6-months.
Assessment of probing pocket depths (PPD, in mm) by using a manual periodontal probe on six sites (mesiobuccal, midbuccal, distobuccal, mesiolingual, midlingual and distolingual) will be performed.
clinical attachment level (CAL)
Time frame: Change from baseline to 6-months.
Assessment of clinical attachment level (CAL, in mm) by using a manual periodontal probe on six sites (mesiobuccal, midbuccal, distobuccal, mesiolingual, midlingual and distolingual) will be performed.

Sponsor's own description

The aim of this study is to evaluate the periodontal outcomes after applying antimicrobial photodynamic therapy with a novel photosensitizer as compared to LASER assisted scaling and root planing alone.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Periodontitis

Currently open trials in the same condition.

NCT07463859 — Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabet · NA · recruiting
NCT07535177 — Gas6 and Soluble MerTK in Periodontal Diseases · recruiting
NCT07491848 — Oral-Periodontal Evaluation and Assessment of Oral Fluid Biomarkers in Patients With Hepatitis B+D · recruiting
NCT07421960 — Investigation of the Relationship Between Periodontitis and Sleep Quality · recruiting
NCT07532694 — Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients · NA · recruiting

Other SVS Institute of Dental Sciences trials

Trials by the same sponsor.

NCT04937023 — Ursodeoxycholic Acid (Udca) as a Local Drug Delivery Agent in the Treatment of Intra-bony Defects · NA · unknown
NCT04361630 — Recombinant Human Fibroblast Growth Factor-2 (rhFGF-2) In Gingival Recession Defects · EARLY_PHASE1 · completed
NCT05342649 — Effect of Two Methods of Soft Tissue Augmentation for Socket Closure on Soft Tissue Landmarks and Ridge Dimensions · NA · completed
NCT04372420 — Bone Morphogenetic Protein-2 In Grade II Furcation Defects. · NA · completed
NCT04368650 — RhBMP-2 in Intrabony Defects - A Randomized Controlled Trial · Phase 2 · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04374383 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by SVS Institute of Dental Sciences
Last refreshed: 5 May 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04374383.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing