Last reviewed · How we verify
NCT04373538
Improving Well-being by Improving Memory for Treatment for Sleep and Circadian Dysfunction
NA trial testing Trans-C for sleep and circadian function + Memory Support in Sleep Disorder in 28 participants. Completed in 25 June 2021.
15 January 2021
Quick facts
| Lead sponsor | University of California, Berkeley |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | health services research |
| Enrollment | 28 |
| Start date | 1 May 2020 |
| Primary completion | 15 January 2021 |
| Estimated completion | 25 June 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Trans-C for sleep and circadian function + Memory Support
Conditions studied
- Sleep Disorder — all drugs for Sleep Disorder →
- Circadian Dysregulation — all drugs for Circadian Dysregulation →
Sponsor
University of California, Berkeley
Who can join
55 and older, any sex, with Sleep Disorder or Circadian Dysregulation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Mental illness is often chronic, severe, and difficult to treat. Though there has been significant progress towards establishing effective and efficient interventions for psychological health problems, many individuals do not gain lasting benefits from these treatments. The Memory Support Intervention (MSI) was developed utilizing existing findings from the cognitive science literature to improve treatment outcomes. In this study, the investigators aim to conduct an open trial that includes individuals 55 years and older to assess if a simplified version of the Memory Support Intervention improves sleep and circadian functioning, reduces functional impairment, and improves patient memory for treatment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Pilot Trial for Midlife and Older Adults: Sleep and Circadian Treatment Plus Memory Support and Boosters.
Sarfan LD, Milner AE, Varghese J, Ovalle Patino E, et al · · 2025 · PMID 41316985 · DOI 10.1080/07317115.2025.2595027
Verify or expand the search:
- PubMed search for NCT04373538
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04373538 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of California, Berkeley
- Last refreshed: 29 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04373538.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing