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NCT04373148

Understanding Immunity to SARS-CoV-2, the Coronavirus Causing COVID-19

Completed Last updated 15 June 2022
What this trial tests

trial testing There is no intervention in Coronavirus in 316 participants. Completed in 31 May 2022.

Timeline
8 April 2020
Primary endpoint
31 May 2022
31 May 2022

Quick facts

Lead sponsorStanford University
StatusCompleted
Study typeOBSERVATIONAL
Enrollment316
Start date8 April 2020
Primary completion31 May 2022
Estimated completion31 May 2022
Sites2 locations across United States

Drugs / interventions tested

Conditions studied

Sponsor

Stanford University

Who can join

2 and older, any sex, with Coronavirus. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to test over time immunity to SARS-CoV-2, a recently identified coronavirus responsible for the 2019 world-wide pneumonia outbreak known as COVID-19. Adults and children diagnosed with COVID-19 as well as controls without COVID-19 will be invited to participate in this study.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

  1. KIR<sup>+</sup>CD8<sup>+</sup> T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19.
    Li J, Zaslavsky M, Su Y, Guo J, et al · · 2022 · cited 225× · PMID 35258337 · DOI 10.1126/science.abi9591
  2. Gut Microbiota Dysbiosis-Immune Hyperresponse-Inflammation Triad in Coronavirus Disease 2019 (COVID-19): Impact of Pharmacological and Nutraceutical Approaches.
    Ferreira C, Viana SD, Reis F. · · 2020 · cited 44× · PMID 33019592 · DOI 10.3390/microorganisms8101514
  3. Anti-nucleocapsid antibody levels and pulmonary comorbid conditions are linked to post-COVID-19 syndrome.
    Jia X, Cao S, Lee AS, Manohar M, et al · · 2022 · cited 33× · PMID 35801588 · DOI 10.1172/jci.insight.156713
  4. Therapeutic Peptides: Recent Advances in Discovery, Synthesis, and Clinical Translation.
    Zheng B, Wang X, Guo M, Tzeng CM. · · 2025 · cited 23× · PMID 40507941 · DOI 10.3390/ijms26115131
  5. Single cell multi-omic analysis identifies key genes differentially expressed in innate lymphoid cells from COVID-19 patients.
    Kaushik A, Chang I, Han X, He Z, et al · · 2024 · cited 5× · PMID 39026668 · DOI 10.3389/fimmu.2024.1374828

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Other trials of There is no intervention

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Other Stanford University trials

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04373148.

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