Last reviewed · How we verify
NCT04372888
Examining Choice Architecture for Genetic Testing Decisions
NA trial testing choice decision frame in Decision Making in 1,012 participants. Completed in 30 March 2020.
26 March 2020
Quick facts
| Lead sponsor | Boston College |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | health services research |
| Enrollment | 1,012 |
| Start date | 11 March 2020 |
| Primary completion | 26 March 2020 |
| Estimated completion | 30 March 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- choice decision frame
- opt-in decision frame
- opt-out decision frame
- enhanced choice (context) decision frame
- enhanced choice (norms) decision frame
- enhanced choice (affect) decision frame
Conditions studied
- Decision Making — all drugs for Decision Making →
Sponsor
Boston College
Who can join
Adults 18 to 64, any sex, with Decision Making. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this application is to gain a deeper understanding of decision-making for genetic testing and identify effective choice-architecture-based strategies to improve decisions in genetic testing. The investigators hypothesize that choice architecture (i.e. framing) affects decision-making for hypothetical genetic testing scenarios.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Framing Effects on Decision-Making for Diagnostic Genetic Testing: Results from a Randomized Trial.
Dwyer AA, Shen H, Zeng Z, Gregas M, et al · · 2021 · cited 7× · PMID 34202935 · DOI 10.3390/genes12060941
Verify or expand the search:
- PubMed search for NCT04372888
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04372888 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Boston College
- Last refreshed: 6 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04372888.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing