NCT04368858: DETECACTI

Towards the Use of Instrumented Tests for Screening the Risk of Falling in Patients With Chronic Illness.

Completed NA Last updated 21 November 2022

What this trial tests

NA trial testing Exploratory physiopathology study, including non-invasive functional explorations carried out in patients with chronic pathology. in Joint Osteoarthritis in 120 participants. Completed in 16 November 2022.

Timeline

28 August 2020

Primary endpoint
16 November 2022

16 November 2022

Quick facts

Lead sponsor	University Hospital, Clermont-Ferrand
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	120
Start date	28 August 2020
Primary completion	16 November 2022
Estimated completion	16 November 2022
Sites	1 location across France

Drugs / interventions tested

• Exploratory physiopathology study, including non-invasive functional explorations carried out in patients with chronic pathology.

Conditions studied

• Joint Osteoarthritis — all drugs for Joint Osteoarthritis →
• Atherosclerosis of the Distal Arteries, Without Gangrene — all drugs for Atherosclerosis of the Distal Arteries, Without Gangrene →
• Parkinson Disease — all drugs for Parkinson Disease →
• Chronic Obstructive Pulmonary Disease, Unspecified — all drugs for Chronic Obstructive Pulmonary Disease, Unspecified →

Sponsor

University Hospital, Clermont-Ferrand

Who can join

Adults 18 to 90, any sex, with Joint Osteoarthritis or Atherosclerosis of the Distal Arteries, Without Gangrene. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In patients with chronic illness, screening for falls and their health consequences are major public health issues. Muscle weakness, gait and balance disorders are among the most common risk factors for falling. Assessing these parameters would thus be a crucial step in the evaluation of the risk of falling, allowing to more precisely orient the management strategy. Combining inertial unit sensors with clinically validated tests can provide additional information to improve the assessment of fall risks. We therefore propose to constitute a monocentric exploratory study, testing a prognostic screening tool, in patients suffering from a chronic pathology, in order to assess the risk of falling in this population.

Considering the relationship between muscle weakness and the risk of falling, we can assume that a deficit in muscle strength will result in less vertical acceleration which could point to a muscle cause of the balance disorder and thus allow a finer detection of the risk of falling. On the other hand, we hypothesize that spinal static disorders in chronic pathologies and in particular osteoarthritis, as well as balance disorders linked to impaired deep sensitivity lead to an increase in oscillations of the trunk when walking which can cause postural balance disorders thus increasing the risk of falling.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Correlation Between Instrumented Timed Up and Go Test Performance and Muscle Strength in Knee and Hip Osteoarthritis: An Exploratory, Cross-Sectional Study.
   Pelletier Visa M, Dobija L, Verdilos A, Mullez A, et al · · 2025 · PMID 41516576 · DOI 10.3390/s26010142