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NCT04362215

Heart Aging When Near Vision Difficulty Begins

Completed Last updated 24 April 2020
What this trial tests

trial testing Subjective accomodation amplitude measurement in Aging in 500 participants. Completed in 15 March 2020.

Timeline
10 September 2019
Primary endpoint
15 March 2020
15 March 2020

Quick facts

Lead sponsorKecioren Education and Training Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment500
Start date10 September 2019
Primary completion15 March 2020
Estimated completion15 March 2020
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Kecioren Education and Training Hospital

Who can join

Adults 49 to 51, any sex, with Aging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Near vision deterioration during aging results from a decrease in accomodation amplitude (AA). Myocardial regeneration is limited, and cardiac aging is an independent risk factor for cardiovascular disease. Thus, the investigators investigated the association between cardiac aging and AA. The subjects (500, mean 50-year-old subjects, with equal males and females) were divided into two groups according to AA measured with a Raf ruler. Biomicroscopy was used to capture images of the lens nucleus in the unaccommodated state, followed by images of a 4 diopter (D) accommodated state. The nucleus diameter change at 1 D accomodation was measured using ImageJ. Cardiac conduction system differences were evaluated using electrocardiography, and cardiac autonomic aging was assessed based on heart rate variability. Myocardial aging was assessed based on diastolic dysfunction.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Heart aging when near vision difficulty begins.
    Koç Ş, Baysal SS. · · 2020 · PMID 32449445 · DOI 10.1080/13685538.2020.1766438

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Other recruiting trials for Aging

Currently open trials in the same condition.

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Data sources for this page

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