Who is sponsoring NCT04357171?

NCT04357171 is sponsored by Russian Society of Colorectal Surgeons.

What drugs are being tested in NCT04357171?

Interventions in NCT04357171: Low anterior resection with protective loop ileostomy, Low anterior resection with protective loop transverse colostomy.

What condition does NCT04357171 study?

NCT04357171 studies Rectal Cancer.

Is NCT04357171 still recruiting?

NCT04357171 is currently completed. Last updated 22 April 2020.

Last reviewed 2020-04-22 · How we verify

NCT04357171: PROTECT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

PReventive cOlostomy vs Ileostomy in Low anTErior reCTal Resection

Completed NA Last updated 22 April 2020

What this trial tests

NA trial testing Low anterior resection with protective loop ileostomy in Rectal Cancer in 202 participants. Completed in 2 February 2020.

Timeline

14 January 2012

Primary endpoint
2 February 2020

2 February 2020

Quick facts

Lead sponsor	Russian Society of Colorectal Surgeons
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	202
Start date	14 January 2012
Primary completion	2 February 2020
Estimated completion	2 February 2020

Drugs / interventions tested

Low anterior resection with protective loop ileostomy
Low anterior resection with protective loop transverse colostomy

Conditions studied

Rectal Cancer — all drugs for Rectal Cancer →

Sponsor

Russian Society of Colorectal Surgeons

Who can join

Adults 18 to 85, any sex, with Rectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The type of preventive intestinal stoma (colostomy/ileostomy) after low anterior rectal resection rectum is still a debate. This study purpose is to demonstrate that preventive loop ileostomy is characterized by a higher readmission rate caused by dehydration, in comparison with the loop colostomy.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Characteristics of Interventional Trials for Patients Living With Intestinal Stoma Registered in ClinicalTrials.gov With a Focus on Inflammatory Bowel Disease.
Vuyyuru SK, Ma C, Sharma T, Nguyen TM, et al · · 2024 · cited 3× · PMID 38135729 · DOI 10.1093/ibd/izad293

Verify or expand the search:

Other recruiting trials for Rectal Cancer

Currently open trials in the same condition.

NCT07528209 — Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer · Phase 3 · recruiting
NCT07537998 — Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a · Phase 2, PHASE3 · recruiting
NCT07501845 — Registry Maastro Applicator · recruiting
NCT07369531 — The Impact of Two-Stage Turnbull-Cutait Pull-Through Coloanal Anastomosis on Stoma-free Survival in Low Rectal Anal-pres · NA · recruiting
NCT07505472 — Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Wit · Phase 2, PHASE3 · recruiting

Other Russian Society of Colorectal Surgeons trials

Trials by the same sponsor.

NCT06119867 — CompariSon Between the EuroPeAn and Japanese pathologiCal InvEstigation for Colon Cancer (SPACE) · Phase 3 · recruiting
NCT05715983 — Comparison of Laser Destruction of Pilonidal Sinus Disease (SILAC) and Bascom II Procedure. · NA · unknown
NCT04364373 — D2 vs D3 Lymph Node Dissection for Left Colon Cancer · NA · recruiting
NCT04361695 — Preemptive Analgesia for Hemorrhoidectomy · NA · unknown
NCT04288349 — IntraopeRativE Use of periNeal Block for Hemorrhoidectomy · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04357171 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Russian Society of Colorectal Surgeons
Last refreshed: 22 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04357171.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing