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NCT04357093
Remineralizing Efficacy of Grape Seed Extract in Management of White Spot Lesion in Post Orthodontic Treated Patients.
NA trial testing Grape seed extract mouthwash in Dental Caries in 40 participants. Completed in 30 August 2021.
10 August 2021
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 10 February 2021 |
| Primary completion | 10 August 2021 |
| Estimated completion | 30 August 2021 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Grape seed extract mouthwash
- Sodium fluoride mouthwash
Conditions studied
- Dental Caries — all drugs for Dental Caries →
Sponsor
Cairo University
Who can join
Adults 13 to 30, any sex, with Dental Caries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial will be conducted to compare the efficacy of grape seed extract oil versus sodium fluoride mouth wash in the management of remineralization in adult patients with white spot lesion over six months.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Optical behavior and marginal discoloration of a single shade resin composite with a chameleon effect: a randomized controlled clinical trial.
Anwar RS, Hussein YF, Riad M. · · 2024 · cited 13× · PMID 38378771 · DOI 10.1038/s41405-024-00184-w
Verify or expand the search:
- PubMed search for NCT04357093
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Cairo University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04357093 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 17 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04357093.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing