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NCT04353544
Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Spontaneous Vaginal Delivery
NA trial testing delayed cord clamping in Post Partum Hemorrhage in 122 participants. Completed in 1 May 2021.
25 February 2021
Quick facts
| Lead sponsor | Federico II University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 122 |
| Start date | 16 April 2020 |
| Primary completion | 25 February 2021 |
| Estimated completion | 1 May 2021 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- delayed cord clamping
Conditions studied
- Post Partum Hemorrhage — all drugs for Post Partum Hemorrhage →
Sponsor
Federico II University
Who can join
Eligibility, female only, with Post Partum Hemorrhage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Policies for timing of cord clamping vary, with early cord clamping generally carried out in the first 60 seconds aLer birth, whereas latercord clamping usually involves clamping the umbilical cord greater than one minute after the birth or when cord pulsation has ceased
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of delayed versus immediate umbilical cord clamping in vaginal delivery at term: A randomized clinical trial.
De Angelis C, Saccone G, Sorichetti E, Alagna M, et al · · 2022 · cited 2× · PMID 35428979 · DOI 10.1002/ijgo.14223
Verify or expand the search:
- PubMed search for NCT04353544
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of delayed cord clamping
Trials testing the same drug.
- NCT05922488 — Effect of Umbilical Cord Milking Versus Clamping in Preterms on Cerebral Oxygenation and Ductus Arteriosus Closure · NA · completed
- NCT04369313 — Effect of DCC on Neonatal Jaundice and Blood Gas Analysis in Infants Born to GDM Mothers · NA · unknown
- NCT03147846 — The Hematologic Impact of Umbilical Cord Milking Versus Deferred Cord Clamping in Premature Neonates. · NA · completed
Other recruiting trials for Post Partum Hemorrhage
Currently open trials in the same condition.
- NCT05488457 — Oxytocin Pharmacokinetics and Pharmacodynamics · Phase 2 · recruiting
- NCT06604325 — Prophylactic Tranexamic Acid To Reduce Blood Loss During Caesarean Delivery. · NA · recruiting
- NCT06577922 — Evaluation of Maternal & Newborn Health Simulation Lab Centers of Excellence in Nepal · NA · recruiting
- NCT05370820 — Prevention of Postpartum Hemorrhage With Tranexamic Acid · Phase 2 · recruiting
Other Federico II University trials
Trials by the same sponsor.
- NCT07437690 — Fall Prevention in Older Adults in an Italian Cohort · not yet recruiting
- NCT07282132 — Evaluation of Real-World Data on Ropeginterferon Alfa-2b in Patients With Polycythemia Vera: Insights From a Multicenter · not yet recruiting
- NCT07280286 — Incidence of Intrauterine Adhesions After Myomectomy With Intrauterine Anti-Adhesion Gel · NA · not yet recruiting
- NCT07374861 — Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy · recruiting
- NCT07314684 — GLP1-RAs Effects on Inflammatory and Endothelial Biomarkers in T2DM · Phase 4 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04353544 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Federico II University
- Last refreshed: 24 August 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04353544.
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