Who is sponsoring NCT04350931?

NCT04350931 is sponsored by Ain Shams University.

What drugs are being tested in NCT04350931?

Interventions in NCT04350931: intradermal injection of BCG Vaccine, placebo.

What condition does NCT04350931 study?

NCT04350931 studies Coronavirus Disease (COVID-19).

Is NCT04350931 still recruiting?

NCT04350931 is currently status unknown. Last updated 20 April 2020.

Last reviewed 2020-04-20 · How we verify

NCT04350931

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Application of BCG Vaccine for Immune-prophylaxis Among Egyptian Healthcare Workers During the Pandemic of COVID-19

Status unknown Phase 3 Last updated 20 April 2020

What this trial tests

Phase 3 trial testing intradermal injection of BCG Vaccine in Coronavirus Disease (COVID-19) in 900 participants. Status unknown.

Timeline

20 April 2020

Primary endpoint
1 October 2020

1 December 2020

Quick facts

Lead sponsor	Ain Shams University
Phase	Phase 3
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	900
Start date	20 April 2020
Primary completion	1 October 2020
Estimated completion	1 December 2020
Sites	1 location across Egypt

Drugs / interventions tested

intradermal injection of BCG Vaccine — full drug profile →
placebo

Conditions studied

Coronavirus Disease (COVID-19) — all drugs for Coronavirus Disease (COVID-19) →

Sponsor

Ain Shams University

Who can join

18 and older, any sex, with Coronavirus Disease (COVID-19). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Phase III Placebo-controlled adaptive multi-centre randomized controlled trial Interventional (Clinical Trial). The study will include nine hundred healthcare workers in the isolation hospitals for COVID-19 cases; they will be randomly assigned to receive either BCG vaccine or normal saline.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

COVID-19: A Review on the Novel Coronavirus Disease Evolution, Transmission, Detection, Control and Prevention.
Sharma A, Ahmad Farouk I, Lal SK. · · 2021 · cited 345× · PMID 33572857 · DOI 10.3390/v13020202
Coronavirus vaccine development: from SARS and MERS to COVID-19.
Li YD, Chi WY, Su JH, Ferrall L, et al · · 2020 · cited 242× · PMID 33341119 · DOI 10.1186/s12929-020-00695-2
COVID-19: Characteristics and Therapeutics.
Chilamakuri R, Agarwal S. · · 2021 · cited 192× · PMID 33494237 · DOI 10.3390/cells10020206
The Long Road Toward COVID-19 Herd Immunity: Vaccine Platform Technologies and Mass Immunization Strategies.
Frederiksen LSF, Zhang Y, Foged C, Thakur A. · · 2020 · cited 164× · PMID 32793245 · DOI 10.3389/fimmu.2020.01817
Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies.
Market M, Angka L, Martel AB, Bastin D, et al · · 2020 · cited 115× · PMID 32655581 · DOI 10.3389/fimmu.2020.01512
100 years of Bacillus Calmette-Guérin immunotherapy: from cattle to COVID-19.
Lobo N, Brooks NA, Zlotta AR, Cirillo JD, et al · · 2021 · cited 114× · PMID 34131332 · DOI 10.1038/s41585-021-00481-1
Is BCG vaccination causally related to reduced COVID-19 mortality?
Miyasaka M. · · 2020 · cited 69× · PMID 32379923 · DOI 10.15252/emmm.202012661
Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines.
Flanagan KL, Best E, Crawford NW, Giles M, et al · · 2020 · cited 64× · PMID 33123165 · DOI 10.3389/fimmu.2020.579250

Verify or expand the search:

Other recruiting trials for Coronavirus Disease (COVID-19)

Currently open trials in the same condition.

NCT06667700 — A Clinical Study of Molnupiravir to Prevent Severe Illness From Coronavirus Disease 2019 (COVID-19) in People Who Are Hi · Phase 3 · recruiting

Other Ain Shams University trials

Trials by the same sponsor.

NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04350931 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
Last refreshed: 20 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04350931.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing