NCT04350814: SCOPE

The Self-Compassion Online - Preventing Depression Trial

Completed NA Last updated 8 May 2024

What this trial tests

NA trial testing Self-Compassion Step by Step in Depression in 158 participants. Completed in 1 May 2024.

Timeline

1 March 2020

Primary endpoint
1 December 2023

1 May 2024

Quick facts

Lead sponsor	University of Regina
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	158
Start date	1 March 2020
Primary completion	1 December 2023
Estimated completion	1 May 2024
Sites	2 locations across Canada

Drugs / interventions tested

• Self-Compassion Step by Step
• Self-Reflection Active Control

Conditions studied

• Depression — all drugs for Depression →

Sponsor

University of Regina

Who can join

Adults 18 to 79, any sex, with Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Purpose: Depression affects 12.6% of Canadians at some point in their life. Depression is associated with staggering personal and economic costs. There are several treatments that have been shown to treat episodes of depression when they occur. Unfortunately, more than half who respond to these treatments go on to re-experience an episode of depression. Even with psychological and pharmacological interventions designed to prevent future episodes, relapse and recurrence of the disorder remain alarmingly high. A patient-focused and self-directed intervention that harnesses the effects of an Eastern-influenced concept, called self-compassion, has shown tremendous promise in treating acute depression. Self-compassion is being moved by one's own suffering, and a desire to alleviate such suffering.

Objectives: In the proposed project, the investigators will examine whether a self-compassion intervention is effective in preventing relapse/recurrence of depression over a 12-month period among people who are at high risk for relapse. The investigators will also examine whether the intervention works to prevent depression by increasing the innate ability to bounce back from stress, a concept known as resilience.

Methodology: 120 participants with a history of depression will be randomly assigned to the self-compassion intervention or a self-assessment reflection condition, and their respective relapse rates will be examined over a period of 12 months.

Importance to Research: This will be the first study to examine the effects of self-compassion as a preventive intervention for depression.

Impact on health: If successful, this new intervention can be used by thousands of people in Saskatchewan and Canada who are at risk for depression relapse.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.