Who is sponsoring NCT04348162?

NCT04348162 is sponsored by National Research Council, Spain.

What drugs are being tested in NCT04348162?

Interventions in NCT04348162: Cocoa flavanols and berries anthocyanins.

What condition does NCT04348162 study?

NCT04348162 studies Healthy Aging.

Is NCT04348162 still recruiting?

NCT04348162 is currently completed. Last updated 16 September 2021.

Last reviewed 2021-09-16 · How we verify

NCT04348162: POLYAGE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Food Anthocyanins and Flavanols as a Strategy for a Healthy Ageing: Cardiovascular Health and Cognitive Performance

Completed NA Last updated 16 September 2021

What this trial tests

NA trial testing Cocoa flavanols and berries anthocyanins in Healthy Aging in 90 participants. Completed in 15 May 2021.

Timeline

15 September 2017

Primary endpoint
1 January 2021

15 May 2021

Quick facts

Lead sponsor	National Research Council, Spain
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	90
Start date	15 September 2017
Primary completion	1 January 2021
Estimated completion	15 May 2021
Sites	1 location across Spain

Drugs / interventions tested

Cocoa flavanols and berries anthocyanins

Conditions studied

Healthy Aging — all drugs for Healthy Aging →

Sponsor

National Research Council, Spain

Who can join

Adults 50 to 85, any sex, with Healthy Aging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study examines the effect of cocoa flavanols, red-berries anthocyanins or a combination of both on markers of cardiovascular health and cognition.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Neurocognitive Effects of Cocoa and Red-Berries Consumption in Healthy Adults.
García-Cordero J, Pino A, Cuevas C, Puertas-Martín V, et al · · 2021 · cited 18× · PMID 35010877 · DOI 10.3390/nu14010001
Regular Consumption of Cocoa and Red Berries as a Strategy to Improve Cardiovascular Biomarkers via Modulation of Microbiota Metabolism in Healthy Aging Adults.
García-Cordero J, Martinez A, Blanco-Valverde C, Pino A, et al · · 2023 · cited 14× · PMID 37242181 · DOI 10.3390/nu15102299
Clinical Insights on Caloric Restriction Mimetics for Mitigating Brain Aging and Related Neurodegeneration.
Trisal A, Singh AK. · · 2024 · cited 9× · PMID 39412683 · DOI 10.1007/s10571-024-01493-2

Verify or expand the search:

Other recruiting trials for Healthy Aging

Currently open trials in the same condition.

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NCT07207044 — FAXAGE: Fasting And Exercise To Slow Aging In Humans · NA · recruiting
NCT07151365 — Plant-based Diets and Healthy Aging · recruiting

Other National Research Council, Spain trials

Trials by the same sponsor.

NCT07508735 — Bioavailability of Phlorotannins and Carotenoids Following the Intake of Crackers Fortified With Seaweed · NA · active not recruiting
NCT06735222 — Bioavailability of Hydroxytyrosol in Humans Co-administered With EPA · NA · completed
NCT07182370 — Polyphenol Metabolism and Personalized Nutrition in Menopause (PolyPause). · NA · active not recruiting
NCT06295913 — Hydroxytyrosol Dietary Supplement and Prevention of Age-Related Diseases · NA · completed
NCT04383639 — Cocoa/Carob Polyphenols and Postprandial Changes in Type 2 Diabetes · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04348162 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by National Research Council, Spain
Last refreshed: 16 September 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04348162.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing