NCT04344119 (ChilblainCOVID) is a clinical trial in Skin Manifestations, sponsored by Centre Hospitalier Universitaire de Nice.

Who is sponsoring NCT04344119?

NCT04344119 is sponsored by Centre Hospitalier Universitaire de Nice.

What condition does NCT04344119 study?

NCT04344119 studies Skin Manifestations, COVID, Chilblains.

Is NCT04344119 still recruiting?

NCT04344119 is currently status unknown. Last updated 20 January 2021.

Last reviewed 2021-01-20 · How we verify

NCT04344119: ChilblainCOVID

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Assessment of Chilbains Occuring During Covid-19 Infection

Status unknown Last updated 20 January 2021

What this trial tests

trial in Skin Manifestations in 30 participants. Status unknown.

Timeline

9 April 2020

Primary endpoint
30 April 2021

30 April 2021

Quick facts

Lead sponsor	Centre Hospitalier Universitaire de Nice
Status	Status unknown
Study type	OBSERVATIONAL
Enrollment	30
Start date	9 April 2020
Primary completion	30 April 2021
Estimated completion	30 April 2021
Sites	1 location across France

Conditions studied

Skin Manifestations — all drugs for Skin Manifestations →
COVID — all drugs for COVID →
Chilblains — all drugs for Chilblains →

Sponsor

Centre Hospitalier Universitaire de Nice

Who can join

Under 90, any sex, with Skin Manifestations or COVID. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Some patients infected by covid-19 develop skin manifestations. These manifestations are still not well known and there pathophysiology remain unclear. Among them, acral manifestation resembling to chilblains appears frequent and quite specific. The aim of this project is to better characterize the cutaneous manifestations occurring during Covid-19 infection with a special focus on chilblains. These acral manifestation could be due to a direct viral effect, but also to microthrombosis or vascularitis. Understanding the pathomechanisms involved could provide interesting clue for understanding not only the skin manifestations but also some of the other systemic symptoms associated to covid-19 infection. This study plan to characterize these acral manifestations by analyzing the clinical and dermoscopic patterns and to correlate them with the non-invasive vascular explorations but also immune and coagulopathy explorations that are done in the CHU of Nice in covid-19 patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Clinical, Laboratory, and Interferon-Alpha Response Characteristics of Patients With Chilblain-like Lesions During the COVID-19 Pandemic.
Hubiche T, Cardot-Leccia N, Le Duff F, Seitz-Polski B, et al · · 2021 · cited 85× · PMID 33237291 · DOI 10.1001/jamadermatol.2020.4324
Relapse of chilblain-like lesions during the second wave of the COVID-19 pandemic: a cohort follow-up.
Hubiche T, Le Duff F, Fontas E, Rapp J, et al · · 2021 · cited 5× · PMID 34128539 · DOI 10.1111/bjd.20584

Verify or expand the search:

Other recruiting trials for Skin Manifestations

Currently open trials in the same condition.

NCT05987163 — Study to Evaluate the Safety and Effectiveness of GP0116 · NA · active not recruiting

Other Centre Hospitalier Universitaire de Nice trials

Trials by the same sponsor.

NCT05897996 — Percutaneous Anastomosis Creation for Hemodialysis Access · NA · withdrawn
NCT07499869 — INNOVATIVE BENEFITS OF A 4D VIRTUAL SIMULATOR · NA · not yet recruiting
NCT07492251 — Upadacitinib in Adult Patients With Erosive Mucosal Lichen Planus and Lichen Planopilaris: a Prospective Multicenter Ran · Phase 2 · not yet recruiting
NCT07511608 — Development of a New Technique for Quantifying Mitochondrial DNA in Single Muscle Fibers · NA · not yet recruiting
NCT07582406 — Codesign, Physical Activity, and Seniors · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04344119 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire de Nice
Last refreshed: 20 January 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04344119.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing