NCT04343079

Intra-operative PET-CT: a Novel Approach to Determine Excision Margins in Lumpectomy Breast Cancer.

Status unknown NA Last updated 23 January 2024

What this trial tests

NA trial testing PET CT in Breast Cancer Female in 100 participants. Status unknown.

Timeline

1 January 2018

Primary endpoint
31 December 2024

31 December 2025

Quick facts

Lead sponsor	University Hospital, Ghent
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	100
Start date	1 January 2018
Primary completion	31 December 2024
Estimated completion	31 December 2025
Sites	1 location across Belgium

Drugs / interventions tested

• PET CT

Conditions studied

• Breast Cancer Female — all drugs for Breast Cancer Female →
• Breast Neoplasms — all drugs for Breast Neoplasms →

Sponsor

University Hospital, Ghent

Who can join

Adults 18 to 85, female only, with Breast Cancer Female or Breast Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Examination of the feasibility of intra-operative pet CT to detect surgical margins in breast conservative surgery to prevent re-excision.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

1. Method for co-registration of high-resolution specimen PET-CT with histopathology to improve insight into radiotracer distributions.
   Maris L, Göker M, Debacker JM, De Man K, et al · · 2024 · cited 2× · PMID 39400788 · DOI 10.1186/s40658-024-00681-9
2. Breast cancer Intraoperative Margin Assessment using specimen PET-CT (BIMAP).
   De Crem AS, Tummers P, Depypere H, Braems G, et al · · 2025 · cited 1× · PMID 41006264 · DOI 10.1038/s41523-025-00818-8
3. Supporting intraoperative margin assessment using deep learning for automatic tumour segmentation in breast lumpectomy micro-PET-CT.
   Maris L, Göker M, De Man K, Van den Broeck B, et al · · 2025 · PMID 40783490 · DOI 10.1038/s41523-025-00797-w