Last reviewed · How we verify
NCT04330391
Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App
NA trial testing Remote dietitian supervised weight loss intervention and mobile app in Arthroplasties, Replacement in 60 participants. Completed in 30 June 2024.
1 June 2023
Quick facts
| Lead sponsor | Brigham and Women's Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 July 2020 |
| Primary completion | 1 June 2023 |
| Estimated completion | 30 June 2024 |
| Sites | 3 locations across United States |
Drugs / interventions tested
- Remote dietitian supervised weight loss intervention and mobile app
Conditions studied
- Arthroplasties, Replacement — all drugs for Arthroplasties, Replacement →
- Weight Loss — all drugs for Weight Loss →
- Nutrition — all drugs for Nutrition →
Sponsor
Brigham and Women's Hospital
Who can join
18 and older, any sex, with Arthroplasties, Replacement or Weight Loss. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this trial is to assess the impact of a 12-week remote dietitian supervised dietary and physical activity weight loss intervention and mobile app for patients with morbid obesity prior to undergoing total joint arthroplasty of the hip or knee. The hypothesis is that that the intervention will result in: 1) greater weight loss than usual care, 2) a higher percentage of patients eligible to undergo surgery by having a body mass index (BMI) below the standard cutoff of 40 kg/m2, and 3) a higher percentage of patients undergoing surgery within six months of study enrollment.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Weight loss before total joint arthroplasty using a remote dietitian and mobile app: study protocol for a multicenter randomized, controlled trial.
Seward MW, Antonelli BJ, Giunta N, Iorio R, et al · · 2020 · cited 19× · PMID 33187535 · DOI 10.1186/s13018-020-02059-w
Verify or expand the search:
- PubMed search for NCT04330391
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04330391 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Brigham and Women's Hospital
- Last refreshed: 9 August 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04330391.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing