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NCT04330066
Impact of Endometrial Compaction in Euploid Frozen Embryo Transfers
trial testing Abdominal ultrasound measurement of the endometrial lining in Infertility, Female in 187 participants. Status unknown.
30 May 2022
Quick facts
| Lead sponsor | Boston IVF |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 187 |
| Start date | 1 September 2020 |
| Primary completion | 30 May 2022 |
| Estimated completion | 30 June 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Abdominal ultrasound measurement of the endometrial lining
Conditions studied
- Infertility, Female — all drugs for Infertility, Female →
Sponsor
Boston IVF
Who can join
Adults 18 to 44, female only, with Infertility, Female. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this pilot study is to evaluate whether a decrease in endometrial thickness (compaction) prior to progesterone exposure (endogenous or exogenous) to the day before a single frozen embryo transfer has an impact on the clinical pregnancy rate with euploid embryos in exogenous hormone and modified natural thaw cycles. Information derived from this study may give insight on ways to improve pregnancy rates in cryo-thaw cycles.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Endometrial compaction does not predict live birth in single euploid frozen embryo transfers: a prospective study.
Shah JS, Vaughan DA, Dodge LE, Leung A, et al · · 2022 · cited 16× · PMID 35357436 · DOI 10.1093/humrep/deac060
Verify or expand the search:
- PubMed search for NCT04330066
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Boston IVF trials
Trials by the same sponsor.
- NCT04917445 — The Impact of the SPIKES Protocol With IVF Patients · NA · completed
- NCT04206800 — Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients · NA · terminated
- NCT04803045 — Does a Brief Intervention Decrease Patient Drop Out Rates? · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04330066 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Boston IVF
- Last refreshed: 11 March 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04330066.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing