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NCT04326907: CAT
Treatment of Complex Anal Fistulas Using Centrifuged Adipose Tissue Containing Progenitor Cells
NA trial testing Autologous centrifuged adipose tissue (CAT) injection after anal fistulectomy in Anal Fistula in 120 participants. Completed in 1 October 2019.
1 May 2019
Quick facts
| Lead sponsor | University Hospital of Ferrara |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 120 |
| Start date | 1 May 2016 |
| Primary completion | 1 May 2019 |
| Estimated completion | 1 October 2019 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Autologous centrifuged adipose tissue (CAT) injection after anal fistulectomy
Conditions studied
- Anal Fistula — all drugs for Anal Fistula →
Sponsor
University Hospital of Ferrara
Who can join
18 and older, any sex, with Anal Fistula. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In the treatment of complex anal fistulas transplant of freshly collected autologous adipose tissue mechanically fragmented or centrifuged adipose tissue (CAT) might be an alternative to in vitro expanded autologous or allogeneic adipose-derived stem cells, showing remarkable efficacy in diverse therapeutic indications. The aim of our study is to evaluate randomly the efficacy and safety of the use of CAT in the healing process of complex anal fistulas, except for Crohn's disease (CD) related fistulas.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Efficacy and Safety of Treatment of Complex Idiopathic Fistula-in-Ano Using Autologous Centrifuged Adipose Tissue Containing Progenitor Cells: A Randomized Controlled Trial.
Ascanelli S, Zamboni P, Campioni D, Grazia Sibilla M, et al · · 2021 · cited 16× · PMID 34016825 · DOI 10.1097/dcr.0000000000001924
Verify or expand the search:
- PubMed search for NCT04326907
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Anal Fistula
Currently open trials in the same condition.
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- NCT06803550 — Effect of Enhanced Recovery After Surgery for Benign Anorectal Conditions · NA · recruiting
- NCT06303752 — Tissue Therapy of Transsphincteric Anal Fistula · Phase 1, PHASE2 · recruiting
- NCT05641844 — A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal · NA · recruiting
Other University Hospital of Ferrara trials
Trials by the same sponsor.
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- NCT06679517 — Observational Study Relating to the Long-term Follow-up of Patients with Severe Aortic Stenosis Evaluated for Percutaneo · enrolling by invitation
- NCT07058896 — Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Severe Gait Impair · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04326907 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital of Ferrara
- Last refreshed: 30 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04326907.
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