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NCT04325789
Rotator Cuff Healing Using a Nanofiber Scaffold in Patients Greater Than 55 Years
NA trial testing nanofiber scaffold in Rotator Cuff Tears in 91 participants. Participants enrolled and being followed up; not accepting new ones.
15 March 2025
Quick facts
| Lead sponsor | Atreon Orthopedics |
|---|---|
| Phase | NA |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 91 |
| Start date | 29 June 2020 |
| Primary completion | 15 March 2025 |
| Estimated completion | 15 March 2025 |
| Sites | 4 locations across United States |
Drugs / interventions tested
- nanofiber scaffold
Conditions studied
- Rotator Cuff Tears — all drugs for Rotator Cuff Tears →
- Full-thickness Rotator Cuff Tears — all drugs for Full-thickness Rotator Cuff Tears →
Sponsor
Atreon Orthopedics
Who can join
55 and older, any sex, with Rotator Cuff Tears or Full-thickness Rotator Cuff Tears. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Randomized controlled trial of patients over the age of 55 treated with and without a nanofiber scaffold during rotator cuff repair.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Polymeric Materials, Advances and Applications in Tissue Engineering: A Review.
Socci MC, Rodríguez G, Oliva E, Fushimi S, et al · · 2023 · cited 38× · PMID 36829712 · DOI 10.3390/bioengineering10020218 -
Designing electrospun fiber platforms for efficient delivery of genetic material and genome editing tools.
Puhl DL, Mohanraj D, Nelson DW, Gilbert RJ. · · 2022 · cited 26× · PMID 35183657 · DOI 10.1016/j.addr.2022.114161 -
Evolving Trends in Nanofibers for Topical Delivery of Therapeutics in Skin Disorders.
Tomar Y, Pandit N, Priya S, Singhvi G. · · 2023 · cited 19× · PMID 37273582 · DOI 10.1021/acsomega.3c00924 -
Implementation of Endogenous and Exogenous Mesenchymal Progenitor Cells for Skeletal Tissue Regeneration and Repair.
Desai S, Jayasuriya CT. · · 2020 · cited 8× · PMID 32759659 · DOI 10.3390/bioengineering7030086
Verify or expand the search:
- PubMed search for NCT04325789
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Rotator Cuff Tears
Currently open trials in the same condition.
- NCT07383038 — Effect of Mobilization With Movement in Patients With Rotator Cuff Lesions · NA · recruiting
- NCT06918041 — FiberLocker® System Augmentation of Rotator Cuff Repairs · NA · recruiting
- NCT06886932 — Pain Education After Rotator Cuff Surgery · recruiting
- NCT07001566 — The Impact of Cervical Radiculopathy on Functionality in Patients Undergoing Rotator Cuff Repair · recruiting
- NCT06733480 — Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04325789 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Atreon Orthopedics
- Last refreshed: 23 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04325789.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing