Last reviewed · How we verify
NCT04324853: HELMVIT
Helminth Infection During Pregnancy on Vitamin D Regulation: HELMVIT Study
trial testing Microscopy ( Urine filtration), UCAA test, qPCR, in Vitamin D Deficiency in 180 participants. Completed in 31 December 2022.
31 December 2022
Quick facts
| Lead sponsor | Centre de Recherche Médicale de Lambaréné |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 180 |
| Start date | 28 January 2019 |
| Primary completion | 31 December 2022 |
| Estimated completion | 31 December 2022 |
| Sites | 1 location across Gabon |
Drugs / interventions tested
- Microscopy ( Urine filtration), UCAA test, qPCR,
- Microscopy (Kato Katz, Coproculture, Harada Mori, MIF), qPCR,
Conditions studied
- Vitamin D Deficiency — all drugs for Vitamin D Deficiency →
- Immunosuppression — all drugs for Immunosuppression →
Sponsor
Centre de Recherche Médicale de Lambaréné — full company profile →
Who can join
Eligibility, female only, with Vitamin D Deficiency or Immunosuppression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Purpose: To examine whether helminth infection during pregnancy alters Vitamin-D-metabolism and reactivity of the child's immune system Hypothesis: Helminth infection during pregnancy is associated with altered Vitamin D levels and Vitamin D receptor expression in the placenta and modified immune reactivity in the infant.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Impact of helminth infections during pregnancy on maternal and newborn Vitamin D and on birth outcomes.
Berry SPD, Honkpèhedji YJ, Ludwig E, Mahmoudou S, et al · · 2024 · cited 2× · PMID 38937587 · DOI 10.1038/s41598-024-65232-9 -
Diagnostic accuracy of plasma cell-free DNA qPCR for Schistosoma haematobium assessed by Bayesian latent class analysis in a cohort of pregnant women from Lambaréné, Gabon.
Hamway Y, Josten T, Abdellatif S, Mukherjee P, et al · · 2026 · PMID 42104414 · DOI 10.1186/s40249-026-01447-4
Verify or expand the search:
- PubMed search for NCT04324853
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Vitamin D Deficiency
Currently open trials in the same condition.
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- NCT07481240 — A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families · NA · recruiting
- NCT07006714 — Preoperative Correction of Vitamin D Deficiency in Total Joint Arthroplasty (TJA) · Phase 4 · active not recruiting
- NCT07200011 — Effect of Vitamin D on the Clinical and Radiographic of Unsplinted Mandibular Implant Overdentures · active not recruiting
Other Centre de Recherche Médicale de Lambaréné trials
Trials by the same sponsor.
- NCT07017803 — Molecular Epidemiology, Strains Genotyping of Multi-drug Resistant Tuberculosis Circulating in Central Africa Region · not yet recruiting
- NCT05905432 — Pan-Malaria Transmission-Blocking Vaccine AnAPN1 · Phase 1 · completed
- NCT05929157 — A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate · Phase 1, PHASE2 · unknown
- NCT05130398 — Safety and Immunogenicity of the rVSVΔG-ZEBOV-GP Ebola Virus Vaccine Candidate in Children Living in Lambaréné, Gabon · Phase 1, PHASE2 · completed
- NCT04847817 — Important Data on COVID-19 Profile in Africa · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04324853 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre de Recherche Médicale de Lambaréné
- Last refreshed: 18 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04324853.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing