NCT04324697 (Shell grafting) is a Phase 4 clinical trial of Horizontal alveolar bone augmentation in Alveolar Bone Resorption, sponsored by October 6 University.

Who is sponsoring NCT04324697?

NCT04324697 is sponsored by October 6 University.

What drugs are being tested in NCT04324697?

Interventions in NCT04324697: Horizontal alveolar bone augmentation.

What condition does NCT04324697 study?

NCT04324697 studies Alveolar Bone Resorption.

Is NCT04324697 still recruiting?

NCT04324697 is currently completed. Last updated 9 June 2020.

Last reviewed 2020-06-09 · How we verify

NCT04324697: Shell grafting

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips

Completed Phase 4 Last updated 9 June 2020

What this trial tests

Phase 4 trial testing Horizontal alveolar bone augmentation in Alveolar Bone Resorption in 10 participants. Completed in 5 September 2019.

Timeline

8 April 2018

Primary endpoint
1 July 2019

5 September 2019

Quick facts

Lead sponsor	October 6 University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	10
Start date	8 April 2018
Primary completion	1 July 2019
Estimated completion	5 September 2019
Sites	1 location across Egypt

Drugs / interventions tested

Horizontal alveolar bone augmentation

Conditions studied

Alveolar Bone Resorption — all drugs for Alveolar Bone Resorption →

Sponsor

October 6 University

Who can join

Adults 18 to 50, any sex, with Alveolar Bone Resorption. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The clinical cases in the present study described the khoury shell technique using an allograft plate and autogenous chips, for horizontal reconstruction of the anterior alveolar ridge in the esthetic zone. Without need to use autogenous bone graft techniques that are characterized by more aggressive surgery.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Anterior Aesthetic Zone Reconstruction with Allogenic Bone Shell and Autogenous Bone Chips - An Evaluative Study.
Karkar KT, Metwally SA, Mohsen KMA. · · 2023 · cited 2× · PMID 37711516 · DOI 10.4103/ams.ams_34_23

Verify or expand the search:

Other recruiting trials for Alveolar Bone Resorption

Currently open trials in the same condition.

NCT07404098 — Efficacy Of Eggshell-Derived Nanohydroxyapatite Based Mineralized Plasmatic Matrix Versus Xenogeneic Based Mineralized P · NA · active not recruiting
NCT05937035 — Histological and Volumetric Evaluation of Customized Allograft Bone Blocks · NA · recruiting
NCT07028606 — Vertical Ridge Augmentation Using Computer-guided Sandwich Osteotomy Technique · Phase 1 · active not recruiting
NCT05577663 — Guided Bone Regeneration in Alveolar Socket · NA · recruiting

Other October 6 University trials

Trials by the same sponsor.

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NCT07305792 — High Tone Power Therapy on Lumbosacral Radiculopathy Patients · NA · completed
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NCT07350655 — Efficacy of Virtual Reality-based Training in Patients With Chronic Non-specific Low Back Pain · NA · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04324697 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by October 6 University
Last refreshed: 9 June 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04324697.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing