Last reviewed · How we verify
NCT04321668: RESYF
Innovative Tool to Analyse Synovial Fluid of Patients With Knee Ostearthritis After IA Injection of Synvisc-one®
NA trial testing Synvisc-One in Knee Osteoarthritis in 13 participants. Completed in 15 February 2022.
1 October 2021
Quick facts
| Lead sponsor | Pulsalys |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 13 |
| Start date | 12 February 2020 |
| Primary completion | 1 October 2021 |
| Estimated completion | 15 February 2022 |
| Sites | 3 locations across Belgium |
Drugs / interventions tested
- Synvisc-One — full drug profile →
Conditions studied
- Knee Osteoarthritis — all drugs for Knee Osteoarthritis →
- Intra-Articular Injection — all drugs for Intra-Articular Injection →
Sponsor
Pulsalys
Who can join
Adults 40 to 80, any sex, with Knee Osteoarthritis or Intra-Articular Injection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The objective of this trial is to assess the clinical pertinence of an innovative analytical tool (SYNODIAG) to analyze the Synovial Fluid (SF) composition and guide the patient treatment in a Proof of Concept (PoC) study using OA patients receiving IA injection of SYNVISC ONE®.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04321668
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Synvisc-One
Trials testing the same drug.
- NCT04045431 — Treatment of Knee Osteoarthritis With PAAG-OA · NA · active not recruiting
- NCT03328728 — Cellular Matrix Device for the Treatment of Mild to Moderate Knee Osteoarthritis · NA · unknown
- NCT03182374 — nSTRIDE APS Versus Hyaluronic Acid for Knee Osteoarthritis · NA · completed
- NCT02674399 — A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis · Phase 2 · completed
Other recruiting trials for Knee Osteoarthritis
Currently open trials in the same condition.
- NCT06906939 — A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression · EARLY_PHASE1 · recruiting
- NCT05823727 — Effects of Collagen Peptide Supplementation on Connective Tissue Remodeling, Functional Outcomes, and Wound Healing Afte · NA · recruiting
- NCT07370480 — Knee Osteoarthritis and Thermal Spa Treatment · NA · recruiting
- NCT07507175 — Gastrocnemius Myofascial Release in Females With Knee Osteoarthritis · NA · recruiting
- NCT07386600 — Dexamethasone vs Dexmedetomidine for iPACK + ACB in TKA · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04321668 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pulsalys
- Last refreshed: 22 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04321668.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing