NCT04320914 is a NA clinical trial of High Intensity LASER Therapy in Osteo Arthritis Knee, sponsored by Maharishi Markendeswar University (Deemed to be University).

Who is sponsoring NCT04320914?

NCT04320914 is sponsored by Maharishi Markendeswar University (Deemed to be University).

What drugs are being tested in NCT04320914?

Interventions in NCT04320914: High Intensity LASER Therapy, Ibuprofen gel phonophoresis.

What condition does NCT04320914 study?

NCT04320914 studies Osteo Arthritis Knee.

Is NCT04320914 still recruiting?

NCT04320914 is currently status unknown. Last updated 14 September 2022.

Last reviewed 2022-09-14 · How we verify

NCT04320914

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

High Intensity Laser Therapy (Classes IV) and Ibuprofen Gel Phonophoresis for Treating Knee Osteoarthritis

Status unknown NA Last updated 14 September 2022

What this trial tests

NA trial testing High Intensity LASER Therapy in Osteo Arthritis Knee in 80 participants. Status unknown.

Timeline

28 September 2020

Primary endpoint
21 May 2023

30 June 2023

Quick facts

Lead sponsor	Maharishi Markendeswar University (Deemed to be University)
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	80
Start date	28 September 2020
Primary completion	21 May 2023
Estimated completion	30 June 2023
Sites	1 location across India

Drugs / interventions tested

High Intensity LASER Therapy
Ibuprofen gel phonophoresis

Conditions studied

Osteo Arthritis Knee — all drugs for Osteo Arthritis Knee →

Sponsor

Maharishi Markendeswar University (Deemed to be University)

Who can join

Adults 45 to 70, any sex, with Osteo Arthritis Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A total of 80 patients with knee osteoarthritis (KOA) aged between fourty five and seventy years will be recruited by simple random sampling to participate in two group, randomized, double blind, controlled study. Recruited patients will be randomly divided in to two groups high intensity-laser therapy (HILT) group and ibuprofen gel phonophoresis (IGP) group. Duration of the treatment will be 8 minutes in one session/knee joint for each day for 3 days/week for 8 weeks.The pain and quality of life will be assessed at the baseline and at the end of 8-week post-intervention period.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparative efficacy of high intensity laser therapy (Class IV) and ibuprofen gel phonophoresis in the treatment of knee osteoarthritis among people living in hilly terrain: A randomized controlled study.
Sharma D, Saini V, Srivastav AK, Samuel AJ. · · 2025 · PMID 41114869 · DOI 10.1007/s10103-025-04613-6

Verify or expand the search:

Other recruiting trials for Osteo Arthritis Knee

Currently open trials in the same condition.

NCT07258693 — Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versus Therapeu · NA · active not recruiting
NCT07141316 — Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty · NA · active not recruiting
NCT06485843 — An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Jo · Phase 2 · recruiting
NCT06965946 — Intermittent Hypoxia-Hyperoxia Combined With Physical Therapy for Knee Osteoarthritis · NA · recruiting
NCT06058169 — Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2) · NA · recruiting

Other Maharishi Markendeswar University (Deemed to be University) trials

Trials by the same sponsor.

NCT06296524 — Effect of Footcore Exercises on Navicular Drop and Plantar Pressure Distribution in Asymptomatic Individual With Flatfoo · NA · unknown
NCT06262074 — Effect of Structured Training Program in Diabetic Patients · NA · unknown
NCT06252480 — Effect of Various Intensities of tDCS on Dual Task Cognitive Functions in Normal Subjects · NA · unknown
NCT06176924 — Effect of tDCS Along With Relaxation Technique on Anxiety Level in Students Preparing for Competitive Exams · NA · unknown
NCT05737498 — Transcranial Direct Current Stimulation (tDCS) on Working Memory in College Going Students · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04320914 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Maharishi Markendeswar University (Deemed to be University)
Last refreshed: 14 September 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04320914.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing