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NCT04320446
Caffeine Increases Maximal Fat Oxidation During Exercise in Endurance-trained Men: is There a Diurnal Variation
NA trial testing Test in the morning in Energy Metabolism in 15 participants. Completed in 30 November 2019.
30 November 2019
Quick facts
| Lead sponsor | Universidad de Granada |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | other |
| Enrollment | 15 |
| Start date | 1 June 2019 |
| Primary completion | 30 November 2019 |
| Estimated completion | 30 November 2019 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Test in the morning
- Test in the afternoon
Conditions studied
- Energy Metabolism — all drugs for Energy Metabolism →
- Athletic Performance — all drugs for Athletic Performance →
Sponsor
Universidad de Granada — full company profile →
Who can join
Adults 18 to 40, male only, with Energy Metabolism or Athletic Performance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Maximal fat oxidation during exercise (MFO) and the intensity of exercise that elicits MFO (Fatmax) has been recognized as potential determinants of endurance performance. The purpose of this study was to determine the possible interaction between the effects of diurnal variation (morning vs. afternoon) and caffeine ingestion on MFO, Fatmax and VO2 max in endurance-trained men. Specifically, the investigators sought to elucidate whether the stimulant actions of caffeine could reverse the decrements of MFO and Fatmax observed in the morning.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Caffeine increases maximal fat oxidation during a graded exercise test: is there a diurnal variation?
Ramírez-Maldonado M, Jurado-Fasoli L, Del Coso J, R Ruiz J, et al · · 2021 · cited 25× · PMID 33413459 · DOI 10.1186/s12970-020-00400-6
Verify or expand the search:
- PubMed search for NCT04320446
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04320446 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad de Granada
- Last refreshed: 25 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04320446.
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