Last reviewed · How we verify
NCT04319406
Comparative Efficacy of Prolotherapy and Dry Needling in Management of ADD
Phase 4 trial testing Prolotherapy in Anterior Disk Displacement TMJ in 50 participants. Status unknown.
5 August 2020
Quick facts
| Lead sponsor | Postgraduate Institute of Dental Sciences Rohtak |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 5 January 2020 |
| Primary completion | 5 August 2020 |
| Estimated completion | 5 September 2020 |
| Sites | 1 location across India |
Drugs / interventions tested
- Prolotherapy — full drug profile →
- Dry needling
Conditions studied
- Anterior Disk Displacement TMJ — all drugs for Anterior Disk Displacement TMJ →
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Who can join
Adults 18 to 60, any sex, with Anterior Disk Displacement TMJ. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pain and trismus caused by Anterior disc displacement ADD of temporomandibular joint (TMJ) are one of the prime concerns for the patients. In the recent times, Inflammatory Prolotherapy has been studied extensively and has produced promising results. In Inflammatory prolotherapy low grade inflammation is induced physiologically by injection of an irritant solution that initiates healing cascade which leads to repair of the joint structures. Thus, the Present study is designed to evaluate the efficacy of dextrose prolotherapy for the treatment of ADD in TMJ.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04319406
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Prolotherapy
Trials testing the same drug.
- NCT07399145 — Comparison of Prolotherapy and Rehabilitation Treatments in Low Back Pain (CPRTLBP) · NA · completed
- NCT07355712 — Combined Effect of Prolotherapy and Personalized Physical Activity on Knee Osteoarthritis Progression · NA · completed
- NCT06700746 — Efficacy of Dextrose Prolotherapy Compare With ESWT in the Treatment of Chronic Rotator Cuff Tendinopathy · NA · completed
- NCT06161038 — Precision Medicine for Nociception, Sngception and Proprioception. · NA · recruiting
- NCT06712329 — Chronic Plantar Fasciitis: Which is More Effective? Prolotherapy/Extracorporeal Shock Wave Therapy? · NA · completed
Other Postgraduate Institute of Dental Sciences Rohtak trials
Trials by the same sponsor.
- NCT07412067 — Healing of Apicomarginal Defects Using Autograft or Allograft With Collagen Membrane · NA · not yet recruiting
- NCT07381595 — Role of Subgingival Instrumentation in Oral Lichen Planus · NA · not yet recruiting
- NCT07300124 — Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis · NA · not yet recruiting
- NCT07506135 — Effect of Aromatherapy on Pain and Anxiety During Orthodontic Extraction of Maxillary Premolars. · NA · completed
- NCT07179835 — To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04319406 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Postgraduate Institute of Dental Sciences Rohtak
- Last refreshed: 24 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04319406.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing