NCT04308967 is a NA clinical trial of balance exercises in Osteo Arthritis Knee, sponsored by Cukurova University.

Who is sponsoring NCT04308967?

NCT04308967 is sponsored by Cukurova University.

What drugs are being tested in NCT04308967?

Interventions in NCT04308967: balance exercises.

What condition does NCT04308967 study?

NCT04308967 studies Osteo Arthritis Knee, Central Sensitisation.

Is NCT04308967 still recruiting?

NCT04308967 is currently completed. Last updated 12 October 2022.

Last reviewed 2022-10-12 · How we verify

NCT04308967

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Central Sensitization in Knee Osteoarthritis

Completed NA Last updated 12 October 2022

What this trial tests

NA trial testing balance exercises in Osteo Arthritis Knee in 40 participants. Completed in 30 April 2021.

Timeline

20 March 2020

Primary endpoint
20 April 2021

30 April 2021

Quick facts

Lead sponsor	Cukurova University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	40
Start date	20 March 2020
Primary completion	20 April 2021
Estimated completion	30 April 2021
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

balance exercises

Conditions studied

Osteo Arthritis Knee — all drugs for Osteo Arthritis Knee →
Central Sensitisation — all drugs for Central Sensitisation →

Sponsor

Cukurova University

Who can join

18 and older, any sex, with Osteo Arthritis Knee or Central Sensitisation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The stimuli that activate nociceptors cause the dorsal horn of the spinal cord neurons to be sensitive to low-intensive afferent stimuli by decreasing the excitation threshold in patients with osteoarthritis. Although painful stimuli disappear, this situation causes pain to continue and a decrease in quality of life. Therefore, central sensitization should be considered and treated in patients with osteoarthritis. Although various pharmacological and electrophysiological agents are used in the treatment of central sensitization, adequate efficacy is not provided in patients with osteoarthritis. The aim of this study is to investigate the effects of balance exercises on central sensitization in patients with knee osteoarthritis.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Exercise for osteoarthritis of the knee.
Lawford BJ, Hall M, Hinman RS, Van der Esch M, et al · · 2024 · cited 37× · PMID 39625083 · DOI 10.1002/14651858.cd004376.pub4
The effect of balance exercises on central sensitization in patients with knee osteoarthritis.
Tirasci E, Sarpel T, Coskun Benlidayi I, Deniz V. · · 2024 · cited 7× · PMID 38492047 · DOI 10.1007/s00296-024-05550-3

Verify or expand the search:

Other trials of balance exercises

Trials testing the same drug.

NCT05447754 — Comparison of the Effects of Robotic Rehabilitation Versus Traditional Balance Training on Balance and Fear of Falling i · NA · unknown

Other recruiting trials for Osteo Arthritis Knee

Currently open trials in the same condition.

NCT07258693 — Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versus Therapeu · NA · active not recruiting
NCT07141316 — Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty · NA · active not recruiting
NCT06485843 — An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Jo · Phase 2 · recruiting
NCT06965946 — Intermittent Hypoxia-Hyperoxia Combined With Physical Therapy for Knee Osteoarthritis · NA · recruiting
NCT06058169 — Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2) · NA · recruiting

Other Cukurova University trials

Trials by the same sponsor.

NCT07464652 — Objectıve Structured Clınıcal Examınatıon Stress For Intravenous Perıpheral Catheterızatıon · NA · not yet recruiting
NCT07458789 — Breastfeeding Education · NA · not yet recruiting
NCT07346482 — Determining the Effect of Midwife-Led Safe Infant Care Training for Pregnant Women on Awareness of Sudden Infant Death S · NA · not yet recruiting
NCT07248904 — The Effect of a Transtheoretical Model-Based Educational Intervention on First-Year Nursing Students' HPV Knowledge, Hea · NA · recruiting
NCT07241949 — Regional Analgesia Techniques for Laparoscopic Cholecystectomy · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04308967 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cukurova University
Last refreshed: 12 October 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04308967.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing