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NCT04308824
Cyanoacrylate to Stop Bleeding After EMR for Large Polyps
NA trial testing clipping in Colorectal Polyp in 76 participants. Status unknown.
2 March 2022
Quick facts
| Lead sponsor | Societa Italiana di Chirurgia ColoRettale |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 76 |
| Start date | 2 February 2019 |
| Primary completion | 2 March 2022 |
| Estimated completion | 2 April 2022 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- clipping
- nebulization of glue
Conditions studied
- Colorectal Polyp — all drugs for Colorectal Polyp →
Sponsor
Societa Italiana di Chirurgia ColoRettale — full company profile →
Who can join
Adults 18 to 85, any sex, with Colorectal Polyp. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Endoscopic resection of large non-pedunculated adenomas is most often performed using the 'lift-and-cut' endoscopic mucosal resection (EMR) technique. This endoscopic technique has a relatively low technical complexity and short-duration and is commonly considered a safe and reliable surgical option, nevertheless several adverse events can occur during or after this procedure. One of the most frequent late complication is the post-procedural bleeding occurring up to 30 days post-polypectomy, which often requires emergency hospitalization and re-intervention. Endoscopic hemostasis of active post procedure bleeding can be achieved using prophylactic clips. Recently, the use on sprayable hemostatic agents have been introduced in the gastrointestinal endoscopical practice. Cyanoacrylate is a liquid tissue adhesive that has been proved to be of some utility in the endoscopic management of gastrointestinal variceal bleeding. In this study the investigators aim to compare the rate of postoperative bleeding between two groups of patients with large colorectal polyps. In the first group it will be performed a prophylactic clipping after the polypectomy and in the other group it will be used cyanoacrylate after clipping.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04308824
- Europe PMC full search
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Related trials
Other recruiting trials for Colorectal Polyp
Currently open trials in the same condition.
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- NCT06193356 — Detection of Endoscopic Resection Scars and Delineation of Recurrence is Trainable · NA · recruiting
- NCT06502704 — Bile Acids and Microbiome in Early Colorectal Carcinogenesis · recruiting
- NCT06447012 — Artificial Intelligence Development for Colorectal Polyp Diagnosis · recruiting
Other Societa Italiana di Chirurgia ColoRettale trials
Trials by the same sponsor.
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- NCT04514666 — VOCs in Kidney and Liver Transplants · NA · unknown
- NCT03729414 — Doppler-guided or Non Doppler-guided Arterial Ligation and Mucopexy for Third Degree Hemorrhoids: That is the Question · NA · unknown
- NCT04407416 — VOCs vs FIT for Colorectal Cancer Screening · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04308824 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Societa Italiana di Chirurgia ColoRettale
- Last refreshed: 17 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04308824.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing