The Effectiveness of Topical Oral Vitamin D Gel in Prevention of Radiation-induced Oral Mucositis

NCT04308161 Phase 2 UNKNOWN

The main aim of this study was to evaluate clinically the effect of topical oral vitamin D gel in comparison to conventional therapy in prevention of radiation - induced oral mucositis

Details

Lead sponsor	Hams Hamed Abdelrahman
Phase	Phase 2
Status	UNKNOWN
Enrolment	45
Start date	2019-11-02
Completion	2020-12

Conditions

• Oral Mucositis Due to Radiation

Interventions

• vitamin D oral gel
• Miconazole Topical Gel
• BBC oral spray
• Oracure gel
• Alkamisr sachets

Primary outcomes

• Changes in severity of oral mucositis at different time points along the study — up to 3 and 6 weeks
  Oral mucositis will be evaluated by the World Health Organization (WHO) scale which record the extent and severity of oral mucositis at the third and sixth week after the first radiotherapy session.

Countries

Egypt