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NCT04308135
Differences Between Patients With Vascular Parkinsonism and Parkinson's Disease
trial testing Neuro-radiological tools: in Vascular Parkinsonism in 104 participants. Completed in 1 April 2022.
1 December 2021
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 104 |
| Start date | 1 September 2019 |
| Primary completion | 1 December 2021 |
| Estimated completion | 1 April 2022 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Neuro-radiological tools:
- cognitive tests
- lab investigations
- Beck depression inventory (BDI)(Arabic version)
- Clinical Tools for Urinary symptoms:
- Freezing of gait questionnaire
- non-motor symptoms scales (NMSS).
- Movement Disorders Society- Unified Parkinson's Disease Rating Scale (MDS-UPDRS):
- ELIZA for alpha-synuclein
- transcranial color-coded duplex(TCCD)
- extracranial carotid duplex
- The Arabic version of Parkinson's Disease Questionnaire( PDQ-39)
Conditions studied
- Vascular Parkinsonism — all drugs for Vascular Parkinsonism →
- Parkinson's Disease — all drugs for Parkinson's Disease →
Sponsor
Ain Shams University
Who can join
40 and older, any sex, with Vascular Parkinsonism or Parkinson's Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Vascular parkinsonism (VP) is defined as the presence of parkinsonian syndrome, evidence of cerebrovascular disease by brain imaging and an established relationship between the two disorders. However, the diagnosis of VP is problematic. This study aims to distinguish VP from Parkinson's disease (PD) in multiple aspects including clinical features as motor ,non motor symptoms ,response to treatment ,cognitive assessments by using multiple scales, neuro-radiological features of magnetic resonance imaging (MRI) and transcranial color-coded duplex (TCCD) findings. This differentiation will have therapeutic and prognostic implications .
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The clinical and neuroimaging differences between vascular parkinsonism and Parkinson's disease: a case-control study.
George P, Roushdy T, Fathy M, Hamid E, et al · · 2024 · cited 7× · PMID 38321372 · DOI 10.1186/s12883-024-03556-9
Verify or expand the search:
- PubMed search for NCT04308135
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Vascular Parkinsonism
Currently open trials in the same condition.
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- NCT05222386 — Community Outreach for Palliative Engagement -- Parkinson Disease · NA · active not recruiting
- NCT03924414 — Trial of Parkinson's And Zoledronic Acid · Phase 4 · active not recruiting
Other Ain Shams University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04308135 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 21 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04308135.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing