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NCT04307303: BOWMAN
Electrical Stimulation of Abdominal Muscles for Bowel Management in People With Spinal Cord Injury
NA trial testing abdominal functional electrical stimulation in Neurogenic Bowel in 36 participants. Completed in 11 June 2025.
30 May 2025
Quick facts
| Lead sponsor | Salisbury NHS Foundation Trust |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 7 July 2021 |
| Primary completion | 30 May 2025 |
| Estimated completion | 11 June 2025 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- abdominal functional electrical stimulation
Conditions studied
- Neurogenic Bowel — all drugs for Neurogenic Bowel →
Sponsor
Salisbury NHS Foundation Trust
Who can join
Adults 18 to 100, any sex, with Neurogenic Bowel. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A well-managed bowel program is an essential part of daily life for many people with a SCI. Nevertheless, constipation is frequently reported (42-95%). Constipation embraces a spectrum of harms including both physical \& psychological distress. Initial exploratory studies suggest abdominal FES may be useful for decreasing overall bowel management time, decreasing colonic transit time and reducing discomfort. The current study will seek to reproduce previous findings in a 12 week study, using overall bowel management time as a benchmark for establishing proof of principle. The study will include 36 people with a spinal cord injury aged 18 and over with an above T12 injury, a complete or incomplete lesion in a medically stable condition, one year or more after injury. Participants will be randomised into two groups. One group will receive abdominal electrical stimulation and the other group low dose abdominal electrical stimulation. Participants will be asked to keep a bowel diary and complete questionnaires examining quality of life and bowel management.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Conservative, physical and surgical interventions for managing faecal incontinence and constipation in adults with central neurological diseases.
Todd CL, Johnson EE, Stewart F, Wallace SA, et al · · 2024 · cited 3× · PMID 39470206 · DOI 10.1002/14651858.cd002115.pub6
Verify or expand the search:
- PubMed search for NCT04307303
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Neurogenic Bowel
Currently open trials in the same condition.
- NCT06515223 — Improving Pelvic Rehabilitation Using Epidural Stimulation After Spinal Cord Injury · NA · recruiting
- NCT06333886 — Use of Point-of-care Neuro-sacral Electrophysiology Following Spinal Cord Injury · active not recruiting
- NCT06351995 — Neostigmine and Glycopyrrolate by Iontophoresis · Phase 3 · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04307303 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Salisbury NHS Foundation Trust
- Last refreshed: 24 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04307303.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing