Last reviewed · How we verify
NCT04306757
Flow Controlled Ventilation in Cardiac Surgery
NA trial testing Evone in Respiration; Artificial in 54 participants. Completed in 2 March 2021.
2 March 2021
Quick facts
| Lead sponsor | Medical University Innsbruck |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 6 March 2020 |
| Primary completion | 2 March 2021 |
| Estimated completion | 2 March 2021 |
| Sites | 1 location across Austria |
Drugs / interventions tested
- Evone
- Primus
Conditions studied
- Respiration; Artificial — all drugs for Respiration; Artificial →
- Positive-Pressure Respiration — all drugs for Positive-Pressure Respiration →
Sponsor
Medical University Innsbruck
Who can join
Adults 18 to 99, any sex, with Respiration; Artificial or Positive-Pressure Respiration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This trial investigates effects of individualized (by compliance guided pressure settings) flow-controlled ventilation compared to best clinical practice pressure controlled ventilation in cardiac surgery requiring cardiopulmonary bypass.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Flow-controlled ventilation - a new and promising method of ventilation presented with a review of the literature.
Bialka S, Palaczynski P, Szuldrzynski K, Wichary P, et al · · 2022 · cited 14× · PMID 35142160 · DOI 10.5114/ait.2022.112889 -
Postoperative pulmonale Komplikationen nach chirurgischen Eingriffen
Spraider P, Abram J. · · 2021
Verify or expand the search:
- PubMed search for NCT04306757
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Evone
Trials testing the same drug.
- NCT06222463 — Power Dissipation in Flow-controlled Ventilation · NA · unknown
- NCT05679635 — Evaluation of Tracheal Pressure During CPAP · NA · completed
- NCT04534933 — Flow Controlled Ventilation in Thoracic Surgery · NA · completed
Other Medical University Innsbruck trials
Trials by the same sponsor.
- NCT07408726 — Monoaxial vs. Polyaxial Percutaneous Hybrid Stabilization · NA · not yet recruiting
- NCT07101107 — Socio-cognitive and Biological Responses to Maltreatment · not yet recruiting
- NCT07419607 — MIGRAFIT: Evaluating a Group Therapy Program Combining Physical Activity, Progressive Muscle Relaxation and Psychoeducat · NA · recruiting
- NCT07434648 — Comparison of Mastectomy Expander Trial · NA · not yet recruiting
- NCT07391683 — Telemedically Assisted Optimization for Heart Failure Patients Before Cardiac Surgery to Improve Perioperative Outcome · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04306757 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medical University Innsbruck
- Last refreshed: 23 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04306757.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing