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NCT04303390
24 Vs 48 Hours of Cefazolin or Cefuroxime as Prophylaxis
Phase 4 trial testing Cefuroxime in Surgical Site Infection in 568 participants. Completed in 31 May 2022.
31 May 2022
Quick facts
| Lead sponsor | Saud Al Babtain Cardiac Center |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 568 |
| Start date | 6 February 2018 |
| Primary completion | 31 May 2022 |
| Estimated completion | 31 May 2022 |
| Sites | 1 location across Saudi Arabia |
Drugs / interventions tested
- Cefuroxime (CEFUROXIME) — full drug profile →
- Cefazolin (CEFAZOLIN) — full drug profile →
- 24 hours
- 48 hours
Conditions studied
- Surgical Site Infection — all drugs for Surgical Site Infection →
Sponsor
Saud Al Babtain Cardiac Center
Who can join
18 and older, any sex, with Surgical Site Infection. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A randomized control trial studying the effect of prophylactic antibiotics to reduce surgical site infections following cardiac surgery in adults using 1st generation cephalosporin (Cefazolin) or 2nd generation cephalosporin (Cefuroxime).
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04303390
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cefuroxime
Trials testing the same drug.
- NCT06527560 — Clinical Trial Comparing Oral Versus Intravenous Cefuroxime in Pregnant Women with Pyelonephritis · Phase 4 · recruiting
- NCT05609240 — Colo-Pro_2: Bolus-continuous Infusion Cefuroxime Prophylaxis for the Prevention of Infections After Colorectal Surgery · Phase 2 · recruiting
- NCT05388747 — Population Pharmacokinetics, Effectiveness and Safety of Cefuroxime in Neonates · unknown
- NCT04470973 — Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients. · unknown
Other recruiting trials for Surgical Site Infection
Currently open trials in the same condition.
- NCT07501897 — Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Followin · NA · recruiting
- NCT07311395 — Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section · NA · recruiting
- NCT06649890 — A Novel Surgical Irrigation Solution in Post-Mastectomy Reconstruction: Evaluating Xperience™ · NA · recruiting
- NCT07005635 — The Effects of Different Time Reminder On Surgical Hand Scrubing · NA · active not recruiting
- NCT07049614 — Comparative Study of Postoperative Surgical Site Infections in Diabetic and Non-Diabetic Patients · active not recruiting
Other Saud Al Babtain Cardiac Center trials
Trials by the same sponsor.
- NCT05210972 — Coronary Artery Disease Severity in Newly Diagnosed Dysglycemia · completed
- NCT04427046 — Acute Myocardial Infarction in Native Versus Non-native Young Population in Saudi Arabia · completed
- NCT05208424 — New Diabetes Mellitus and Pre-Diabetes With First-time Diagnosed Coronary Artery Disease · completed
- NCT05208398 — Apixaban in Patients With Left Ventricular Thrombus · Phase 3 · completed
- NCT04572061 — Emergency Coronary Artery Bypass Graft in Acute Myocardial Infarction · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04303390 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Saud Al Babtain Cardiac Center
- Last refreshed: 11 April 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04303390.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing