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NCT04297800: GECO-PD

Gait Characteristics and Cognitive Evolution in Parkinson Disease

Completed Last updated 8 January 2025
What this trial tests

trial in Parkinson's Disease in 60 participants. Completed in 31 December 2024.

Timeline
9 November 2019
Primary endpoint
30 November 2023
31 December 2024

Quick facts

Lead sponsorFROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS
StatusCompleted
Study typeOBSERVATIONAL
Enrollment60
Start date9 November 2019
Primary completion30 November 2023
Estimated completion31 December 2024
Sites3 locations across Italy

Conditions studied

Sponsor

FROM- Fondazione per la Ricerca Ospedale di Bergamo- ETS — full company profile →

Who can join

Adults 55 to 74, any sex, with Parkinson's Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Parkinson's disease (PD) is a chronic progressive nervous system disease with gradual motor impairment. Cognitive dysfunction is common in PD, even in the early stages, and it is characterized by impairments in executive, attention, memory, language and visuospatial function. Motor symptoms, in particular, alterations in gait, have been studied in clinical practice to assess disease progression, and its response to treatments, both farmacological and physiotherapeutic. Recent research on wearable technology in PD has shown that motor tests can be automated using wearable technology to eliminate human supervision and patient-reported data. Particularly, the quantitative gait analysis by using inertial devices has been proposed as a sensitive tool to longitudinally monitor gait worsening, response to dopaminergic treatment over time and cognitive dysfunction in PD patients. The aim of this prospective multicente observational study is to investigate whether the dysfunction of specific gait parameters may be correlated to cognitive impairment (Attention/Executive Function Domain) in a cohort of ambulatory PD patients followed for 3 years.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Comparing the Informative Value of 2-Minute Segments of the 6-Minute Walk Test: Insights into a Prospective Study on Parkinson's Disease.
    Zangari R, Brighina L, Pilotto A, Carioli G, et al · · 2025 · cited 1× · PMID 41305283 · DOI 10.3390/s25227076

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Other recruiting trials for Parkinson's Disease

Currently open trials in the same condition.

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Trials by the same sponsor.

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