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NCT04292340

Anti-SARS-CoV-2 Inactivated Convalescent Plasma in the Treatment of COVID-19

Status unknown Last updated 3 March 2020
What this trial tests

trial in Coronavirus in 15 participants. Status unknown.

Timeline
1 February 2020
Primary endpoint
31 July 2020
31 December 2020

Quick facts

Lead sponsorShanghai Public Health Clinical Center
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment15
Start date1 February 2020
Primary completion31 July 2020
Estimated completion31 December 2020
Sites1 location across China

Conditions studied

Sponsor

Shanghai Public Health Clinical Center

Who can join

Eligibility, any sex, with Coronavirus. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is still no effective antiviral drugs and vaccines against SARS-CoV-2 yet now. This is an obsevational study, the investigators collected the clinical information and clinical outcomes of the COVID-19 patients using anti-2019-nCoV inactivated convalescent plasma.The study is to evaluate the efficacy and safety of anti-2019-nCoV inactivated convalescent plasma in the treatment of COVID-19 pneumonia.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?
    Liu B, Li M, Zhou Z, Guan X, et al · · 2020 · cited 507× · PMID 32291137 · DOI 10.1016/j.jaut.2020.102452
  2. The epidemiology, diagnosis and treatment of COVID-19.
    Zhai P, Ding Y, Wu X, Long J, et al · · 2020 · cited 461× · PMID 32234468 · DOI 10.1016/j.ijantimicag.2020.105955
  3. COVID-19: Transmission, prevention, and potential therapeutic opportunities.
    Lotfi M, Hamblin MR, Rezaei N. · · 2020 · cited 447× · PMID 32474009 · DOI 10.1016/j.cca.2020.05.044
  4. Treatment with convalescent plasma for COVID-19 patients in Wuhan, China.
    Ye M, Fu D, Ren Y, Wang F, et al · · 2020 · cited 265× · PMID 32293713 · DOI 10.1002/jmv.25882
  5. Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review.
    Piechotta V, Chai KL, Valk SJ, Doree C, et al · · 2020 · cited 148× · PMID 32648959 · DOI 10.1002/14651858.cd013600.pub2
  6. Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review.
    Valk SJ, Piechotta V, Chai KL, Doree C, et al · · 2020 · cited 126× · PMID 32406927 · DOI 10.1002/14651858.cd013600
  7. Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review.
    Piechotta V, Iannizzi C, Chai KL, Valk SJ, et al · · 2021 · cited 106× · PMID 34013969 · DOI 10.1002/14651858.cd013600.pub4
  8. Adjunct Immunotherapies for the Management of Severely Ill COVID-19 Patients.
    Bonam SR, Kaveri SV, Sakuntabhai A, Gilardin L, et al · · 2020 · cited 91× · PMID 32562483 · DOI 10.1016/j.xcrm.2020.100016

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Other recruiting trials for Coronavirus

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Data sources for this page

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