Last reviewed · How we verify
NCT04292340
Anti-SARS-CoV-2 Inactivated Convalescent Plasma in the Treatment of COVID-19
trial in Coronavirus in 15 participants. Status unknown.
31 July 2020
Quick facts
| Lead sponsor | Shanghai Public Health Clinical Center |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 15 |
| Start date | 1 February 2020 |
| Primary completion | 31 July 2020 |
| Estimated completion | 31 December 2020 |
| Sites | 1 location across China |
Conditions studied
- Coronavirus — all drugs for Coronavirus →
Sponsor
Shanghai Public Health Clinical Center
Who can join
Eligibility, any sex, with Coronavirus. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
There is still no effective antiviral drugs and vaccines against SARS-CoV-2 yet now. This is an obsevational study, the investigators collected the clinical information and clinical outcomes of the COVID-19 patients using anti-2019-nCoV inactivated convalescent plasma.The study is to evaluate the efficacy and safety of anti-2019-nCoV inactivated convalescent plasma in the treatment of COVID-19 pneumonia.
Publications & conference data
8 peer-reviewed publications reference this trial (live from Europe PMC):
-
Can we use interleukin-6 (IL-6) blockade for coronavirus disease 2019 (COVID-19)-induced cytokine release syndrome (CRS)?
Liu B, Li M, Zhou Z, Guan X, et al · · 2020 · cited 507× · PMID 32291137 · DOI 10.1016/j.jaut.2020.102452 -
The epidemiology, diagnosis and treatment of COVID-19.
Zhai P, Ding Y, Wu X, Long J, et al · · 2020 · cited 461× · PMID 32234468 · DOI 10.1016/j.ijantimicag.2020.105955 -
COVID-19: Transmission, prevention, and potential therapeutic opportunities.
Lotfi M, Hamblin MR, Rezaei N. · · 2020 · cited 447× · PMID 32474009 · DOI 10.1016/j.cca.2020.05.044 -
Treatment with convalescent plasma for COVID-19 patients in Wuhan, China.
Ye M, Fu D, Ren Y, Wang F, et al · · 2020 · cited 265× · PMID 32293713 · DOI 10.1002/jmv.25882 -
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review.
Piechotta V, Chai KL, Valk SJ, Doree C, et al · · 2020 · cited 148× · PMID 32648959 · DOI 10.1002/14651858.cd013600.pub2 -
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a rapid review.
Valk SJ, Piechotta V, Chai KL, Doree C, et al · · 2020 · cited 126× · PMID 32406927 · DOI 10.1002/14651858.cd013600 -
Convalescent plasma or hyperimmune immunoglobulin for people with COVID-19: a living systematic review.
Piechotta V, Iannizzi C, Chai KL, Valk SJ, et al · · 2021 · cited 106× · PMID 34013969 · DOI 10.1002/14651858.cd013600.pub4 -
Adjunct Immunotherapies for the Management of Severely Ill COVID-19 Patients.
Bonam SR, Kaveri SV, Sakuntabhai A, Gilardin L, et al · · 2020 · cited 91× · PMID 32562483 · DOI 10.1016/j.xcrm.2020.100016
Verify or expand the search:
- PubMed search for NCT04292340
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Coronavirus
Currently open trials in the same condition.
- NCT04772170 — Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies · recruiting
- NCT05868239 — Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study · NA · recruiting
- NCT04359836 — A Study to Explore the Role of Gut Flora in COVID-19 Infection · recruiting
- NCT04376034 — Convalescent Plasma Collection and Treatment in Pediatrics and Adults · Phase 3 · recruiting
- NCT04568148 — COVID-19 Biorepository · active not recruiting
Other Shanghai Public Health Clinical Center trials
Trials by the same sponsor.
- NCT07526363 — Real-world Cohort Study of Antiretroviral Therapy in HIV Patients With Opportunistic Infections · not yet recruiting
- NCT06940375 — Incidence of Liver Disease-Related Outcomes in People With HIV · recruiting
- NCT06926569 — Single High-dose of Liposomal Amphotericin B in Combination With B/F/TAF for HIV/AIDS-associated Talaromycosis · NA · not yet recruiting
- NCT06768697 — Safety and Immunogenicity Evaluation of the Recombinant Flagellin Protein Adjuvant · EARLY_PHASE1 · not yet recruiting
- NCT05129189 — Functional Cure Study of Anti-PD-L1 Antibody ASC22 in Combination With Chidamide in HIV-infected Patients With Antiviral · Phase 2 · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04292340 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shanghai Public Health Clinical Center
- Last refreshed: 3 March 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04292340.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing