Who is sponsoring NCT04291339?

NCT04291339 is sponsored by Yonsei University.

What drugs are being tested in NCT04291339?

Interventions in NCT04291339: High-flow nasal oxygen technique, Mask ventilation technique.

Is NCT04291339 still recruiting?

NCT04291339 is currently completed. Last updated 1 June 2021.

Last reviewed 2021-06-01 · How we verify

NCT04291339

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison of the Efficacy of High-flow Nasal Oxygen Therapy and Facial Mask Ventilation on the Increase of the Oxygen Reserve Index During Anesthetic Induction

Completed NA Last updated 1 June 2021

What this trial tests

NA trial testing High-flow nasal oxygen technique in Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia in 198 participants. Completed in 12 January 2021.

Timeline

11 November 2020

Primary endpoint
12 January 2021

12 January 2021

Quick facts

Lead sponsor	Yonsei University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	198
Start date	11 November 2020
Primary completion	12 January 2021
Estimated completion	12 January 2021
Sites	1 location across South Korea

Drugs / interventions tested

High-flow nasal oxygen technique
Mask ventilation technique

Conditions studied

Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia — all drugs for Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia →

Sponsor

Yonsei University

Who can join

19 and older, any sex, with Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to compare the ability of oxygenation with high-flow nasal oxygen therapy and mask ventilation technique for induction of anesthesia in adult patients who are planning to undergo surgery under general anesthesia.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: a randomised controlled trial.
Park S, Kim SY, Kim MS, Park WK, et al · · 2023 · cited 7× · PMID 37161369 · DOI 10.1186/s12871-023-02126-9
Comparison of preoxygenation efficiency measured by the oxygen reserve index between high-flow nasal oxygenation and facemask ventilation: A randomized controlled trial
Park S, Kim SY, Kim M, Park WK, et al · · 2022 · DOI 10.21203/rs.3.rs-1426001/v1

Verify or expand the search:

Other Yonsei University trials

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04291339 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Yonsei University
Last refreshed: 1 June 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04291339.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing