NCT04289766

Focal Muscle Vibration on Upper Limb Function in Subacute Post-stroke Patients

Completed NA Last updated 21 April 2021

What this trial tests

NA trial testing Conventional Treatment in Stroke, Subacute in 106 participants. Completed in 20 April 2021.

Timeline

26 February 2020

Primary endpoint
20 April 2021

20 April 2021

Quick facts

Lead sponsor	Riphah International University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	106
Start date	26 February 2020
Primary completion	20 April 2021
Estimated completion	20 April 2021
Sites	1 location across Pakistan

Drugs / interventions tested

• Conventional Treatment — full drug profile →
• Focal Muscle Vibration (120Hz)
• Focal Muscle Vibration (60Hz)

Conditions studied

• Stroke, Subacute — all drugs for Stroke, Subacute →

Sponsor

Riphah International University

Who can join

Adults 35 to 65, any sex, with Stroke, Subacute. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Stroke is the second leading cause of death, accounting for 11.13 % of total deaths, and the main cause of disability worldwide. The major type of stroke is ischemic, which occurs in about 87% of all stroke cases Stroke has different risk factors, which can be grouped into modifiable and non-modifiable risk factors. Major risk factors for stroke include age, history of cerebrovascular event, smoking, alcohol consumption, physical inactivity, hypertension, diabetes mellitus, cardiovascular diseases, obesity, metabolic syndrome, diet, nutrition, and genetic risk factors. Many new technique used for rehabilitation after stroke includes Constraint-Induced Movement Therapy for Arm or Leg Paralysis, Mirror Therapy for Hand Recovery, Harness the Relentless Force etc. Segmental muscle vibration (SMV) is also a new technique and effective to decrease the hyper-toned muscles spasticity but still less work done on it. SMV with different frequencies have different effects for both flaccid and spastic patients of all 3 stages of stroke. In our study we will work with 60hz and 120hz frequencies to reduce the spasticity of upper limb and improves their functional level.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Wearable Focal Muscle Vibration Improves Upper Limb Function in People with Sub-acute Stroke
   Niazi IK, Amjad I, Farooq I, Shafi H, et al · · 2024 · DOI 10.1101/2024.11.11.24317091