NCT04285450 is a NA clinical trial of Vitamin K in Diabetes Mellitus, Type 2, sponsored by Cairo University.

Who is sponsoring NCT04285450?

NCT04285450 is sponsored by Cairo University.

What drugs are being tested in NCT04285450?

Interventions in NCT04285450: Vitamin K, Placebo.

What condition does NCT04285450 study?

NCT04285450 studies Diabetes Mellitus, Type 2.

Is NCT04285450 still recruiting?

NCT04285450 is currently completed. Last updated 25 January 2023.

Last reviewed 2023-01-25 · How we verify

NCT04285450

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Clinical Effect of Vitamin K Administration in Type 2 Diabetic Patients

Completed NA Last updated 25 January 2023

What this trial tests

NA trial testing Vitamin K in Diabetes Mellitus, Type 2 in 106 participants. Completed in 30 May 2022.

Timeline

27 October 2019

Primary endpoint
1 March 2022

30 May 2022

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	106
Start date	27 October 2019
Primary completion	1 March 2022
Estimated completion	30 May 2022
Sites	1 location across Egypt

Drugs / interventions tested

Vitamin K — full drug profile →
Placebo

Conditions studied

Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →

Sponsor

Cairo University

Who can join

Adults 18 to 65, any sex, with Diabetes Mellitus, Type 2. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this study is to examine the possible clinical effects associated with vitamin K supplementation on the glycemic control, insulin sensitivity and lipid profile of type II diabetic patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities.
Jadhav N, Ajgaonkar S, Saha P, Gurav P, et al · · 2022 · cited 52× · PMID 35774605 · DOI 10.3389/fphar.2022.896920
The effect of vitamin K4 supplementation on insulin resistance in individuals with type 2 diabetes: a double-blind randomised placebo-controlled clinical trial.
Ali AM, Abbassi MM, Sabry NA, Fawzi M, et al · · 2023 · cited 3× · PMID 37552330 · DOI 10.1007/s00394-023-03215-8

Verify or expand the search:

Other trials of Vitamin K

Trials testing the same drug.

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NCT03363815 — A Study to Evaluate the Effect of Multiple Doses of CC-90001 on the Pharmacokinetics of Omeprazole, Midazolam, Warfarin, · Phase 1 · completed
NCT01636557 — A Study to Evaluate the Effect of a Single Dose of CNTO 136 (Sirukumab) on CYP450 Enzyme Activities After Subcutaneous A · Phase 1 · completed

Other recruiting trials for Diabetes Mellitus, Type 2

Currently open trials in the same condition.

NCT07415954 — A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 · Phase 2 · recruiting
NCT07532863 — A Real-world Study to Investigate Cardiovascular Risk Profile Among Newly Diagnosed Type 2 Diabetes Mellitus (T2DM) Part · recruiting
NCT07336329 — Continuous Glucose Monitoring in Non-Insulin Treated Type 2 Diabetes: Continuous vs. Periodic Use · NA · recruiting
NCT07242469 — A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006) · Phase 1 · recruiting
NCT07444203 — Transformative Research in Diabetic Nephropathy 2.0 · recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04285450 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 25 January 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04285450.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing