NCT04283591 is a NA clinical trial of Acupuncture Treatment in Post-stroke Depression, sponsored by Istanbul Physical Medicine Rehabilitation Training and Research Hospital.

What drugs are being tested in NCT04283591?

Interventions in NCT04283591: Acupuncture Treatment, Conventional Rehabilitation Programme.

What condition does NCT04283591 study?

NCT04283591 studies Post-stroke Depression, Anxiety Disorders.

Is NCT04283591 still recruiting?

NCT04283591 is currently completed. Last updated 9 February 2021.

Last reviewed 2021-02-09 · How we verify

NCT04283591

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effectiveness of Acupuncture Treatment for Post-Stroke Depression and Anxiety Disorder.

Completed NA Last updated 9 February 2021

What this trial tests

NA trial testing Acupuncture Treatment in Post-stroke Depression in 54 participants. Completed in 1 December 2020.

Timeline

1 August 2019

Primary endpoint
30 November 2020

1 December 2020

Quick facts

Lead sponsor	Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	54
Start date	1 August 2019
Primary completion	30 November 2020
Estimated completion	1 December 2020
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Acupuncture Treatment
Conventional Rehabilitation Programme

Conditions studied

Post-stroke Depression — all drugs for Post-stroke Depression →
Anxiety Disorders — all drugs for Anxiety Disorders →

Sponsor

Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Who can join

Adults 18 to 80, any sex, with Post-stroke Depression or Anxiety Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Poststroke depression is seen with a frequency of up to 30%. Drug options for depression and accompanying sleep problems are limited; In addition, effective doses cannot be increased depending on the comorbidities of the patients and the side effect profiles and drug interactions of the drugs used. Acupuncture has been used in Chinese traditional medicine for more than 2000 years and there are findings that it has positive effects in post-stroke depression and anxiety disorders. The aim of this study is to examine the effectiveness and reliability of acupuncture treatment in depression and anxiety disorders developing after stroke and to reduce the need for multiple drugs and / or high-dose medication in the treatment of these complications. The hypothesis of the study: Acupuncture is an effective and reliable treatment method for depression and anxiety disorders in stroke patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Autophagy regulates inflammation in intracerebral hemorrhage: Enemy or friend?
Fu K, Xu W, Lenahan C, Mo Y, et al · · 2022 · cited 28× · PMID 36726453 · DOI 10.3389/fncel.2022.1036313
Effectiveness of acupuncture treatment in post-stroke depression and anxiety disorders: a prospective, randomized, controlled, single-blind study.
Kalaoğlu E, Kesiktaş FN, Bucak ÖF, Atasoy M, et al · · 2024 · cited 3× · PMID 39587915 · DOI 10.1177/09645284241298294

Verify or expand the search:

Other trials of Acupuncture Treatment

Trials testing the same drug.

NCT04528472 — Acute Ischemic Apoplexy Syndrome Specificity and Acupuncture Intervention Research · NA · unknown
NCT04859686 — Acupuncture and Mindfulness Based Stress Reduction for Wellness · NA · completed

Other Istanbul Physical Medicine Rehabilitation Training and Research Hospital trials

Trials by the same sponsor.

NCT07435935 — Bone Myoregulation Reflex and Postural Control in Vitamin D Deficiency · not yet recruiting
NCT07308795 — The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease · recruiting
NCT07367126 — Neuropathic Pain in Knee Osteoarthritis: Pain Severity and Functional Status · recruiting
NCT07386145 — Frequency and Voluntary Contraction-Dependent Activation of Tonic Vibration Reflex and Bone Myoregulation Reflex · NA · completed
NCT07408570 — FREQUENCY-DEPENDENT SOLEUS REFLEX MODULATION DURING WHOLE-BODY VIBRATION · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04283591 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Last refreshed: 9 February 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04283591.

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