NCT04283266 is a NA clinical trial of Synbiotic in Constipation, sponsored by Vesale Pharmaceutica.

Who is sponsoring NCT04283266?

NCT04283266 is sponsored by Vesale Pharmaceutica.

What drugs are being tested in NCT04283266?

Interventions in NCT04283266: Synbiotic, Placebo.

What condition does NCT04283266 study?

NCT04283266 studies Constipation.

Is NCT04283266 still recruiting?

NCT04283266 is currently completed. Last updated 3 April 2020.

Last reviewed 2020-04-03 · How we verify

NCT04283266

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of a Synbiotic Containing Fructo-oligosaccharides and Bifidobacteria in Middle-aged Adults

Completed NA Last updated 3 April 2020

What this trial tests

NA trial testing Synbiotic in Constipation in 27 participants. Completed in 31 January 2019.

Timeline

12 June 2016

Primary endpoint
29 October 2018

31 January 2019

Quick facts

Lead sponsor	Vesale Pharmaceutica
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	27
Start date	12 June 2016
Primary completion	29 October 2018
Estimated completion	31 January 2019

Drugs / interventions tested

Synbiotic — full drug profile →
Placebo

Conditions studied

Constipation — all drugs for Constipation →

Sponsor

Vesale Pharmaceutica

Who can join

Adults 50 to 70, any sex, with Constipation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to evaluate the impact of a synbiotic containing fructo-oligosaccharides (FOS) and Bifidobacteria (VES002 LMG P-28149) on intestinal transit in middle-aged subjects characterized by a low number of defecations per week.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Improvement of gastrointestinal discomfort and inflammatory status by a synbiotic in middle-aged adults: a double-blind randomized placebo-controlled trial.
Neyrinck AM, Rodriguez J, Taminiau B, Amadieu C, et al · · 2021 · cited 22× · PMID 33514774 · DOI 10.1038/s41598-020-80947-1

Verify or expand the search:

Other trials of Synbiotic

Trials testing the same drug.

NCT07515443 — The Effects of a Commercially Available Synbiotic on the Gut Microbiome and Cardiometabolic Health: A Randomized Double- · NA · completed
NCT06901739 — Therapeutic Potential of a Synbiotic to Improve Mental Health in Subjects With Obesity. · NA · recruiting
NCT06396689 — NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood · NA · not yet recruiting
NCT06300060 — Synbiotic Supplementation in Cyclists · NA · completed
NCT06722443 — Impact of Nutritional Intervention With Probiotics and Prebiotics on Obesity. · NA · enrolling by invitation

Other recruiting trials for Constipation

Currently open trials in the same condition.

NCT07462481 — Probiotic Improve Constipation · NA · recruiting
NCT07466914 — Constipation in Children With Cerebral Palsy · active not recruiting
NCT07215351 — Impact of the Inno Cleanse Dietary Supplement on Gut Health and Associated Variables in Healthy Men and Women · NA · recruiting
NCT07135362 — The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement · NA · recruiting
NCT07091084 — A Study of Herbal Supplements in Cancer Survivors With Constipation · NA · recruiting

Other Vesale Pharmaceutica trials

Trials by the same sponsor.

NCT03601429 — Dietary Supplementation of Lactogyn in Women With Bacterial Vaginosis · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04283266 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Vesale Pharmaceutica
Last refreshed: 3 April 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04283266.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing