Last reviewed · How we verify
NCT04282603: NSMH
Nutritional Strategies for Metabolic Health in Aging
Phase 1, PHASE2 trial testing Weight Loss and Weight Maintenance in Sarcopenic Obesity in 6 participants. Terminated before completion.
31 December 2021
Quick facts
| Lead sponsor | University of Alaska Fairbanks |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 6 |
| Start date | 18 April 2019 |
| Primary completion | 31 December 2021 |
| Estimated completion | 31 December 2021 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Weight Loss and Weight Maintenance
Conditions studied
- Sarcopenic Obesity — all drugs for Sarcopenic Obesity →
Sponsor
University of Alaska Fairbanks
Who can join
Adults 60 to 80, any sex, with Sarcopenic Obesity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sarcopenic obesity in older individuals presents a clinical conundrum without an effective therapeutic strategy. This study will determine the impact of precision amino acid delivery as part of a meal replacement (EMR) during weight loss on the preservation of lean tissue and improvements in metabolic health and physical function in older obese adults. Following weight loss, the investigators will examine whether one serving/day of EMR will sustain the above stated benefits.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Gut dysbiosis and age-related neurological diseases; an innovative approach for therapeutic interventions.
Holmes A, Finger C, Morales-Scheihing D, Lee J, et al · · 2020 · cited 43× · PMID 32755639 · DOI 10.1016/j.trsl.2020.07.012
Verify or expand the search:
- PubMed search for NCT04282603
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Sarcopenic Obesity
Currently open trials in the same condition.
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- NCT06600581 — Safety and Efficacy of IMM01-STEM Against Placebo on Muscle Performance in Seniors With Obesity and Muscle Weakness · Phase 2 · active not recruiting
- NCT06826963 — Feasibility and Effectiveness of Eccentric Exercise in Sarcopenic Older Adults with Heart Failure: a Pilot Study · NA · recruiting
- NCT06822504 — Prevalence of Sarcopenic Obesity in COPD · recruiting
Other University of Alaska Fairbanks trials
Trials by the same sponsor.
- NCT03986632 — Tundra Gifts: Harvesting Local And Regional Resources To Prevent Obesity Among Alaska Native Children In Remote, Underse · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04282603 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alaska Fairbanks
- Last refreshed: 14 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04282603.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing