NCT04281628 is a Phase 4 clinical trial of Ketamine group: in Ketamine, sponsored by Cairo University.

Who is sponsoring NCT04281628?

NCT04281628 is sponsored by Cairo University.

What drugs are being tested in NCT04281628?

Interventions in NCT04281628: Ketamine group:, Control group.

Is NCT04281628 still recruiting?

NCT04281628 is currently completed. Last updated 30 July 2020.

Last reviewed 2020-07-30 · How we verify

NCT04281628

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparison Between Low-dose Ketamine Infusion and Intravenous Morphine

Completed Phase 4 Last updated 30 July 2020

What this trial tests

Phase 4 trial testing Ketamine group: in Ketamine in 80 participants. Completed in 20 June 2020.

Timeline

21 February 2019

Primary endpoint
20 May 2020

20 June 2020

Quick facts

Lead sponsor	Cairo University
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	diagnostic
Enrollment	80
Start date	21 February 2019
Primary completion	20 May 2020
Estimated completion	20 June 2020
Sites	1 location across Egypt

Drugs / interventions tested

Ketamine group: — full drug profile →
Control group — full drug profile →

Conditions studied

Ketamine — all drugs for Ketamine →

Sponsor

Cairo University

Who can join

Adults 18 to 50, female only, with Ketamine. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ketamine is an antagonist of N-methyl-d-aspartate (NMDA) receptor that not only abolishes peripheral afferent noxious stimulation, but it may also prevent central sensitization of nociceptors as shown in animal studies with excellent analgesic property even in subanesthetic doses. It is readily available and is being used currently, even by non-Anesthesiologists, to provide "sedation" for minor procedures.(.. Low-dose ketamine infusion in the perioperative period has shown to produce analgesia and decrease the requirements of opioid analgesics.. In obstetrics, it is being used as an adjunct to an inadequately functioning spinal anesthesia for caesarean section, as an induction agent for cesarean section and also to provide analgesia during labor in intermittent boluses.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Ketamine

Currently open trials in the same condition.

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NCT07181564 — Anesthesia Techniques, Neuroprotection and Surgical Field in FESS Under Controlled Hypotension · NA · recruiting
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NCT06511908 — Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resi · Phase 2 · recruiting
NCT06752759 — Nebulized Ketamine for the Treatment of Major Depressive Disorder in an Inpatient Setting · Phase 3 · recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04281628 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 30 July 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04281628.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing