NCT04276948 is a NA clinical trial of NAD3 in Aging, sponsored by The Center for Applied Health Sciences, LLC.

Who is sponsoring NCT04276948?

NCT04276948 is sponsored by The Center for Applied Health Sciences, LLC.

What drugs are being tested in NCT04276948?

Interventions in NCT04276948: NAD3.

Is NCT04276948 still recruiting?

NCT04276948 is currently completed. Last updated 14 November 2022.

Last reviewed 2022-11-14 · How we verify

NCT04276948

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of NAD3 Supplementation on Biomarkers of Aging

Completed NA Last updated 14 November 2022

What this trial tests

NA trial testing NAD3 in Aging in 45 participants. Completed in 30 May 2021.

Timeline

8 June 2020

Primary endpoint
29 January 2021

30 May 2021

Quick facts

Lead sponsor	The Center for Applied Health Sciences, LLC
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	45
Start date	8 June 2020
Primary completion	29 January 2021
Estimated completion	30 May 2021
Sites	1 location across United States

Drugs / interventions tested

NAD3

Conditions studied

Aging — all drugs for Aging →

Sponsor

The Center for Applied Health Sciences, LLC

Who can join

Adults 40 to 60, any sex, with Aging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a randomized, parallel-group, placebo-controlled, clinical trial in middle-aged and older male and female subjects from Ohio. Subjects will take an over-the-counter dietary supplement or a placebo for 12 weeks. Outcome measures will include body weight, systolic and diastolic blood pressure, standard blood chemistries (e.g. chemistry panel, lipid panel, CBC with differential), changes in mood, vitality, energy, fatigue, productivity, digestive wellness (via anchored Visual Analogue Scales).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop.
Espinoza SE, Khosla S, Baur JA, de Cabo R, et al · · 2023 · cited 19× · PMID 37325957 · DOI 10.1093/gerona/glad034
Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications.
Banerjee P, Olmsted-Davis EA, Deswal A, Nguyen MT, et al · · 2022 · cited 8× · PMID 35801078 · DOI 10.20517/jca.2022.13

Verify or expand the search:

Other trials of NAD3

Trials testing the same drug.

NCT06219161 — The Acute Effect of a Theacrine-based Supplement on Mobilization of Various Stem Cell Populations. · NA · completed

Other recruiting trials for Aging

Currently open trials in the same condition.

NCT02831335 — Technical Development of Multi-Parametric Renocerebral MRI · recruiting
NCT07099053 — Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging · recruiting
NCT07504068 — Effects of Physical Exercise and a Nutritional Supplement on Body Composition, Metabolic Function, and Overall Health in · NA · recruiting
NCT07525453 — Effects of Three Different Exercise Programs on Dynamic Balance in Community-Dwelling Older Adults · NA · recruiting
NCT07500727 — Skeletal Muscle Aging and Responsiveness in Aged People With MS · NA · recruiting

Other The Center for Applied Health Sciences, LLC trials

Trials by the same sponsor.

NCT06700785 — A Pharmacokinetic Comparison of Three Butyrate Products · NA · completed
NCT06106620 — Effects of a Multi-Ingredient Dietary Supplement on Blood and Breath Alcohol Levels · NA · completed
NCT06062186 — Acute Effects of Naturally Occurring Tea and Coffee-based Ingredients on Cognitive Performance · NA · completed
NCT06048640 — Effects of Dynamine Ingestion on Various Indices of Sustained Energy · NA · completed
NCT05657314 — Effects of Pea Proteins on Muscle Damage and Recovery · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04276948 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The Center for Applied Health Sciences, LLC
Last refreshed: 14 November 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04276948.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing