Last reviewed · How we verify
NCT04276766: ENIH-MPS
Exploring the Effect of Inorganic Nitrates on the Human Microvascular Physiology - a Pilot Study.
NA trial testing Crossover intervention in Aging in 25 participants. Completed in 1 January 2018.
1 December 2016
Quick facts
| Lead sponsor | Sheffield Hallam University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 25 |
| Start date | 1 June 2015 |
| Primary completion | 1 December 2016 |
| Estimated completion | 1 January 2018 |
Drugs / interventions tested
- Crossover intervention
Conditions studied
- Aging — all drugs for Aging →
Sponsor
Sheffield Hallam University
Who can join
Adults 18 to 75, any sex, with Aging. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
We conducted a randomised, placebo-controlled, double blind, cross-over, trial to examine the short-term effect of concentrated beetroot juice on vascular outcomes in a young (18-35 years) and older group (55-75 years). The study included a run-in period of one day preceding the test day. A wash-out period of at least 7 days was implemented to ensure to avoid a carry-over effect of the interventions.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
No effect of nitrate-rich beetroot juice on microvascular function and blood pressure in younger and older individuals: a randomised, placebo-controlled double-blind pilot study.
Rogerson D, Aguilar Mora FA, Young JS, Klonizakis M. · · 2022 · cited 6× · PMID 35352014 · DOI 10.1038/s41430-022-01115-4
Verify or expand the search:
- PubMed search for NCT04276766
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04276766 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sheffield Hallam University
- Last refreshed: 19 February 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04276766.
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