Who is sponsoring NCT04276402?

NCT04276402 is sponsored by Wroclaw Medical University.

What drugs are being tested in NCT04276402?

Interventions in NCT04276402: Irradiation of implants with 808nm laser.

What condition does NCT04276402 study?

NCT04276402 studies Malocclusion, Angle Class II.

Is NCT04276402 still recruiting?

NCT04276402 is currently completed. Last updated 19 February 2020.

Last reviewed 2020-02-19 · How we verify

NCT04276402

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Photobiomodulation by 808nm Diode Laser on the Stability of Orthodontic Mini-implants.

Completed NA Last updated 19 February 2020

What this trial tests

NA trial testing Irradiation of implants with 808nm laser in Malocclusion, Angle Class II in 22 participants. Completed in 2 November 2019.

Timeline

5 July 2019

Primary endpoint
12 October 2019

2 November 2019

Quick facts

Lead sponsor	Wroclaw Medical University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	22
Start date	5 July 2019
Primary completion	12 October 2019
Estimated completion	2 November 2019
Sites	1 location across Poland

Drugs / interventions tested

Irradiation of implants with 808nm laser

Conditions studied

Malocclusion, Angle Class II — all drugs for Malocclusion, Angle Class II →

Sponsor

Wroclaw Medical University

Who can join

Adults 18 to 60, any sex, with Malocclusion, Angle Class II. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study aimed to evaluate the influence of a 635nm diode laser on the stability of orthodontic mini-implants in vitro, as well as mini-implants failure rate (mini-implant loss) and patients pain level after the treatment. A randomized clinical split-mouth trial was concluded with 22 subjects (14 women, 8 men), 44 orthodontic mini-implants with a diameter 1.4mm and length of 10mm. Mini-implants were placed between teeth 3 and 4; and 13 and 14 (Universal Numbering System), in the area of the attached gingiva, 2 mm below mucogingival junction.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effect of 808 nm Semiconductor Laser on the Stability of Orthodontic Micro-Implants: A Split-Mouth Study.
Matys J, Flieger R, Gedrange T, Janowicz K, et al · · 2020 · cited 15× · PMID 32423127 · DOI 10.3390/ma13102265

Verify or expand the search:

Other recruiting trials for Malocclusion, Angle Class II

Currently open trials in the same condition.

NCT05950581 — Treatment of Skeletal Class II Malocclusion With Modified Twin-Block Appliance With Clear Plates · NA · recruiting
NCT06743360 — Microanalysis of Changes in 3D Geometry of Orthodontic Mini-implants · active not recruiting
NCT06297109 — Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery · NA · active not recruiting

Other Wroclaw Medical University trials

Trials by the same sponsor.

NCT07413419 — Evaluation of Remote Motivational Interviewing for Disease Management in Heart Failure Patients and Their Carers · NA · not yet recruiting
NCT07159932 — Poland Integrated Medicines Management (PL-IMM) - Study Assessing the Provision of Complex Clinical Pharmacy Services to · NA · not yet recruiting
NCT07141745 — Electroporation vs. Radiofrequency Ablation Guided by 3D Imaging in Repeat Procedures for Atrial Fibrillation · NA · recruiting
NCT07099885 — Simple Urine Composition-based Personalized Algorithm for Effective Congestion Relief in Decompensated Heart Failure · NA · recruiting
NCT07157475 — Vascular Complications in Patients Undergoing Peripheral Revascularization and Taking SGLT-2 Inhibitors · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04276402 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Wroclaw Medical University
Last refreshed: 19 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04276402.

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