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NCT04276194
Vertebral Body Sparing Craniospinal Irradiation for Pediatric Patients With Cancer of the Central Nervous System
NA trial testing Intensity-Modulated Proton Therapy in Malignant Central Nervous System Neoplasm in 10 participants. Completed in 9 February 2024.
3 November 2021
Quick facts
| Lead sponsor | Emory University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 10 |
| Start date | 16 December 2019 |
| Primary completion | 3 November 2021 |
| Estimated completion | 9 February 2024 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Intensity-Modulated Proton Therapy
- Magnetic Resonance Imaging
Conditions studied
- Malignant Central Nervous System Neoplasm — all drugs for Malignant Central Nervous System Neoplasm →
Sponsor
Emory University
Who can join
Adults 3 to 18, any sex, with Malignant Central Nervous System Neoplasm. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This trial studies the feasibility of using intensity modulated proton therapy to deliver craniospinal irradiation while avoiding the bones of the vertebral column. Intensity modulated proton therapy is an advanced radiation therapy modality that uses high energy protons to kill cancer cells and shrink tumors, and may reduce the side effects of treatment by reducing radiation exposure to the spinal column.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04276194
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Malignant Central Nervous System Neoplasm
Currently open trials in the same condition.
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Other Emory University trials
Trials by the same sponsor.
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- NCT07405476 — Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative I · Phase 2 · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04276194 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Emory University
- Last refreshed: 21 March 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04276194.
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