NCT04273009 is a NA clinical trial of Renew VS PTNS in Faecal Incontinence, sponsored by London North West Healthcare NHS Trust.

Who is sponsoring NCT04273009?

NCT04273009 is sponsored by London North West Healthcare NHS Trust.

What drugs are being tested in NCT04273009?

Interventions in NCT04273009: Renew VS PTNS.

What condition does NCT04273009 study?

NCT04273009 studies Faecal Incontinence, Pelvic Floor Disorders.

Is NCT04273009 still recruiting?

NCT04273009 is currently completed. Last updated 17 February 2020.

Last reviewed 2020-02-17 · How we verify

NCT04273009

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Optimising Treatments for Faecal Incontinence

Completed NA Last updated 17 February 2020

What this trial tests

NA trial testing Renew VS PTNS in Faecal Incontinence in 50 participants. Completed in 11 September 2018.

Timeline

15 December 2016

Primary endpoint
11 August 2018

11 September 2018

Quick facts

Lead sponsor	London North West Healthcare NHS Trust
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	double
Primary purpose	treatment
Enrollment	50
Start date	15 December 2016
Primary completion	11 August 2018
Estimated completion	11 September 2018

Drugs / interventions tested

Renew VS PTNS

Conditions studied

Faecal Incontinence — all drugs for Faecal Incontinence →
Pelvic Floor Disorders — all drugs for Pelvic Floor Disorders →

Sponsor

London North West Healthcare NHS Trust — full company profile →

Who can join

18 and older, any sex, with Faecal Incontinence or Pelvic Floor Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of the study is to directly compare two medical treatments for faecal incontinence: Renew™ Anal Insert and Percutaneous Tibial Nerve Stimulation (PTNS) for a period of 12 weeks. Both are routinely used in our practice.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Randomized Pilot Study: Anal Inserts Versus Percutaneous Tibial Nerve Stimulation in Patients With Fecal Incontinence.
Leo CA, Thomas GP, Hodgkinson JD, Leeuwenburgh M, et al · · 2021 · cited 6× · PMID 33399411 · DOI 10.1097/dcr.0000000000001913

Verify or expand the search:

Other recruiting trials for Faecal Incontinence

Currently open trials in the same condition.

NCT07126327 — Peristeen Light Explorative Clinical Investigation · NA · recruiting
NCT06143072 — CArE for OAsI Study: Care Pathways and Anorectal Evaluation for OASI Associated Incontinence · recruiting
NCT06601985 — Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer. · active not recruiting
NCT05245565 — Effects of Modified Precision Functional Sphincter-Preserving Surgery (PPS) on Ultralow Rectal Cancer · recruiting
NCT04918329 — Functional Digestive Disorders Observatory · recruiting

Other London North West Healthcare NHS Trust trials

Trials by the same sponsor.

NCT07271264 — A Randomised Paired Design Study of Texture and Colour Enhancement Imaging (TXI) Versus High-definition White Light Endo · NA · recruiting
NCT07298655 — 3D Contrast Enhanced Microvascular Ultrasound of Carotid Atherosclerosis for the Detection of Carotid Plaque Neo-Revascu · NA · recruiting
NCT07208214 — Texture and Colour Enhancement Imaging (TXI) Versus Dye Chromoendoscopy for Dysplasia Detection in IBD Surveillance. · NA · not yet recruiting
NCT05583968 — Efficiency of AI Reporting (EAIR). · withdrawn
NCT06447961 — PSYLIVED: the Psychological Impacts of Living With an Inherited Colorectal Cancer Predisposition Syndrome · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04273009 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by London North West Healthcare NHS Trust
Last refreshed: 17 February 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04273009.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing