NCT04272814

Compression Therapy for Acute Lower Limb Cellulitis

Terminated NA Last updated 17 February 2020

What this trial tests

NA trial testing Compression therapy in Lower Limb Cellulitis in 2 participants. Terminated before completion.

Timeline

11 July 2018

Primary endpoint
4 April 2019

4 April 2019

Quick facts

Lead sponsor	University Hospital Plymouth NHS Trust
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	2
Start date	11 July 2018
Primary completion	4 April 2019
Estimated completion	4 April 2019
Sites	1 location across United Kingdom

Drugs / interventions tested

• Compression therapy
• initial clinical assessment

Conditions studied

• Lower Limb Cellulitis — all drugs for Lower Limb Cellulitis →

Sponsor

University Hospital Plymouth NHS Trust

Who can join

18 and older, any sex, with Lower Limb Cellulitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Initiating early compression therapy in the treatment of lower limb cellulitis for adults admitted to the acute hospital to improve patient outcomes - a pilot study

Cellulitis is a skin infection that results in oedema (additional fluid within tissues), erythema (redness) and variable levels of skin damage. Patients generally present with malaise, pain and if a lower limb is affected they have difficulty mobilising and weight bearing. Patients within this organisation are often referred to the tissue viability service only after significant skin damage has occurred (even thought they are receiving appropriate antibiotic therapy). At this point they will be offered an established plan of care that includes compression therapy if it can be tolerated however at present less than 50% of those being admitted are referred.

Despite compression therapy being well proven in oedema management there is no data available to support or reject the early application in lower limb cellulitis. There is also a lack of information about the impact of early intervention in quality of life for patients in this specific group.

This study has been developed in order to determine the feasibility of being able to undertake a wider trial which would evaluate the outcomes of patients with acute lower limb cellulitis treated with compression therapy versus standard care.

The objectives of the study would be to test the procedures and data collection tools being considered for use in a wider study. This would include collection of quality outcome questionnaires, limb circumference measurements and photography as well as recruitment of participants, the follow up processes and participant attrition. Secondary objectives would be linked to quality of life outcome measures and would determine oedema reduction (and its impact on quality of life), the average number of beddays compared to a historical cohort and to determine recurrence within the study period.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.