NCT04272229

Cognitive Function and Autonomic Regulation in Patients With Migraine

Completed NA Last updated 28 April 2021

What this trial tests

NA trial testing Cognition in Migraine Disorders in 100 participants. Completed in 15 December 2020.

Timeline

15 January 2020

Primary endpoint
15 December 2020

15 December 2020

Quick facts

Lead sponsor	Fortaleza University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	factorial
Masking	none
Primary purpose	other
Enrollment	100
Start date	15 January 2020
Primary completion	15 December 2020
Estimated completion	15 December 2020
Sites	1 location across Brazil

Drugs / interventions tested

• Cognition
• Sympathetic Nervous System
• Concentratio and Attention

Conditions studied

• Migraine Disorders — all drugs for Migraine Disorders →

Sponsor

Fortaleza University

Who can join

Adults 18 to 60, any sex, with Migraine Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Individuals with migraine have impaired cognitive function and worse autonomic function compared to individuals without migraine. Objective: To evaluate the autonomic function and cognition in young individuals with migraine compared to healthy individuals without migraine. Methods: Cross-sectional study will be carried out at University of Fortaleza with individuals with previous migraines diagnoses and healthy volunteers without migraines. Volunteers of both sexes, aged between 18 and 60 years, clinically diagnosed with migraine or not, who have not undergone any type of drug treatment for at least three months and who accept to participate in the research will be enrolled in the research. Individuals who have comorbidities such as hypertension and Diabetes mellitus (type I and II), respiratory, cardiac and/or chronic vascular diseases, have suffered any significant facial trauma, have a cognitive problem or dysfunction associated with cognition, or have suffered any episode of stroke or transient ischemic attack prior to conducting this research will not be enrolled. Participants will be assessed through cognitive tests, and autonomic function such as Neck Disability Index, Migraine Disability Assessment Questionnaire, Stroop Colo test, digit symbol substitution test, Addenbrooke's cognitive examination, mini-mental state examination, Montreal Cognitive Assessment, Trail Making Test A and B and reaction time test and by MindWave Mobile® devices and Polar V800®.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.